Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Thorac Cancer. 2020 Jun;11(6):1752-1757. doi: 10.1111/1759-7714.13424. Epub 2020 Apr 14.
Since its outbreak in December 2019 in China, the novel coronavirus disease (COVID-19) has rapidly spread and affected several countries. It has resulted in a difficult situation for cancer patients owing to the risks of the epidemic situation outbreak as well as cancer. Patients with cancer are more likely than the general population to contract COVID-19 because of the systemic immunosuppressive status caused by malignant diseases or anticancer treatment. Lung cancer has the highest morbidity and mortality in China and the world. Most patients with lung cancer are smokers with poor underlying lung conditions and low immunity, thus it is vital to protect them from epidemic diseases during cancer treatment. It is necessary to provide individualized medical treatment and management of treatment-related adverse events for patients with lung cancer based on patients' conditions and regional epidemic patterns. KEY POINTS: Significant findings of the study During the outbreak of COVID-19, taking patients' conditions and regional epidemic patterns into consideration, providing appropriate individualized treatment strategies for lung cancer patients with different stages is an urgent requirement. What this study adds Based on the characteristics of lung cancer, this article aims to provide recommendations and suggestions of individualized treatment strategies and management of common adverse events for patients with lung cancer during the epidemic period of COVID-19.
自 2019 年 12 月在中国爆发以来,新型冠状病毒病(COVID-19)迅速传播并影响了多个国家。由于疫情爆发和癌症的风险,癌症患者的处境变得艰难。由于恶性肿瘤或抗肿瘤治疗引起的全身性免疫抑制状态,癌症患者比一般人群更容易感染 COVID-19。肺癌在中国和世界的发病率和死亡率最高。大多数肺癌患者是吸烟者,肺部基础条件差,免疫力低,因此在癌症治疗期间必须保护他们免受传染病的侵害。根据患者的病情和地区流行模式,为肺癌患者提供个体化的治疗和治疗相关不良事件的管理至关重要。
研究的主要发现
在 COVID-19 爆发期间,考虑到患者的病情和地区流行模式,为不同阶段的肺癌患者提供适当的个体化治疗策略是当务之急。
本研究的新增内容
基于肺癌的特点,本文旨在为 COVID-19 流行期间肺癌患者提供个体化治疗策略和常见不良事件管理的建议和意见。