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阿曼首批中东呼吸综合征冠状病毒群:是时候采取行动了。

The first clusters of Middle East respiratory syndrome coronavirus in Oman: Time to act.

机构信息

Office of Health Affairs, Ministry of Health, Oman.

Directorate Health Services, North Al Batinah Governorate, Ministry of Health, Oman.

出版信息

J Infect Public Health. 2020 May;13(5):679-686. doi: 10.1016/j.jiph.2020.03.002. Epub 2020 Apr 16.

DOI:10.1016/j.jiph.2020.03.002
PMID:32307315
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7162632/
Abstract

INTRODUCTION

Middle East respiratory syndrome coronavirus (MERS-CoV), is an emerging infectious disease of growing global importance. This review describes the latest MERS-CoV clusters and the first cases of nosocomial transmission within health care facilities in Oman. We have highlighted lessons learned and proposed steps to prevent healthcare-associated infections.

METHODS

A descriptive analysis of MERS-CoV cases was conducted between January 23 and February 16, 2019. The data from officials and other published sources used.

RESULTS

Thirteen laboratory-confirmed cases of MERS-CoV were reported from three simultaneous clusters from two governorates without an epidemiological link between the clusters. Two clusters were reported from North Al Batinah Governorate, with nine cases (69%) and 1 cluster from South Ash Sharqiyah Governorate with four cases (31%). In total, four deaths were reported (case fatality rate 31%). Four cases (31%) reported were household contacts from the first cluster, 3 (23%) were nosocomial transmission in health care facilities (two for first and one from the second cluster) and 7 (54%) were community-acquired cases.

CONCLUSIONS

The first local clusters of MERS-CoV reported with evidence suggestive of healthcare and household-associated transmission. Early diagnosis and strict implementation of infection control measures remain fundamental in preventing and managing MERS-CoV infection.

摘要

简介

中东呼吸综合征冠状病毒(MERS-CoV)是一种新兴的传染病,具有日益重要的全球意义。本综述描述了最近在阿曼发生的 MERS-CoV 集群以及医疗机构内首次发生的医院感染病例。我们强调了从中吸取的教训,并提出了预防医源性感染的措施。

方法

对 2019 年 1 月 23 日至 2 月 16 日期间的 MERS-CoV 病例进行了描述性分析。使用了官方和其他已发表来源的数据。

结果

报告了来自三个同时发生的集群的 13 例实验室确诊的 MERS-CoV 病例,这些集群之间没有流行病学联系。两个集群来自北巴提奈省,有 9 例(69%),一个集群来自南舍哈里夫省,有 4 例(31%)。总共有 4 人死亡(病死率 31%)。报告的 4 例(31%)是第一个集群的家庭接触者,3 例(23%)是医疗机构内的医院感染(其中 2 例来自第一个集群,1 例来自第二个集群),7 例(54%)是社区获得性病例。

结论

首次报告了 MERS-CoV 的本地集群,有证据表明存在医疗机构和家庭传播。早期诊断和严格执行感染控制措施仍然是预防和管理 MERS-CoV 感染的基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763e/7162632/b9f1098b5339/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763e/7162632/cba5002727c6/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763e/7162632/dfbf64184803/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763e/7162632/b9f1098b5339/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763e/7162632/cba5002727c6/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763e/7162632/dfbf64184803/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763e/7162632/b9f1098b5339/gr3_lrg.jpg

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