Department of Social Medicine and Health Management, School of Public Health, Hangzhou Medical College, Hangzhou, Zhejiang, China.
School of Basic Medical Sciences & Forensic Medicine, Hangzhou Medical College, Hangzhou, Zhejiang, China.
J Med Virol. 2020 Oct;92(10):1948-1955. doi: 10.1002/jmv.25906. Epub 2020 May 22.
Under the outbreak of COVID-19, it was urgent to analyze the cases from clinical features and epidemiological factors, as well as understand the effectiveness of measures taken on disease prevent and control. A retrospective study was applied for descriptive analysis of clinical features and epidemiological factors of confirmed cases in four cities of Zhejiang. The Onset-admission interval was calculated and plotted as well. The provincial measures regarding the response of COVID-19 were summed up and sorted out. The distribution and sex and age were under normality distribution, and the age of 20 to 80 were all in risk of developing the disease. Clinical features of fever and cough were found mostly happen on patients. More than half of the patients had image changed on chest from reported data. The factor of closely contacted with confirmed cases was the most cause to the disease. The median onset-admission interval was 6 days in Zhejiang province. As of the efficient health system, COVID-19 had been successfully prevented and controlled in Zhejiang. Males and females were all vulnerable to COVID-19. Preventing contact with confirmed cases could largely avoid the disease to happen. The government should take emergent and effective measures to prevent and treatment of the pandemic disease.
在 COVID-19 爆发期间,迫切需要从临床特征和流行病学因素分析病例,并了解疾病防控措施的效果。本研究采用回顾性研究对浙江省四个城市确诊病例的临床特征和流行病学因素进行描述性分析。计算并绘制发病-入院间隔,总结和梳理浙江省应对 COVID-19 的省级措施。分布和性别及年龄呈正态分布,20-80 岁的人群都有患病风险。发热和咳嗽是最常见的临床症状。从报告数据来看,超过一半的患者胸部有影像学改变。与确诊病例密切接触是发病的最主要原因。浙江省的中位发病-入院间隔为 6 天。由于有效的卫生系统,COVID-19 在浙江省得到了成功的预防和控制。男性和女性都容易感染 COVID-19。预防与确诊病例的接触可以大大避免疾病的发生。政府应采取紧急有效的措施来预防和治疗这种大流行疾病。