Ulubelen A, Evren N, Tuzlaci E, Johansson C
Faculty of Pharmacy, University of Istanbul, Turkey.
J Nat Prod. 1988 Nov-Dec;51(6):1178-83. doi: 10.1021/np50060a021.
From the root extracts of Salvia hypargeia, in addition to the known diterpenoids cryptanol and horminone, six new abietane diterpenoids were isolated. The structures of the new and the known compounds were established by spectral data. The new compounds, hypargenins A, B, C, D, and F, showed antibacterial activity, while hypargenin F was also active against Mycobacterium tuberculosis. Hypargenin E did not exhibit antibacterial activity.
