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新冠病毒在意大利北部传播:污染的作用如何?

SARS-CoV-2 spread in Northern Italy: what about the pollution role?

机构信息

Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Policlinico Umberto I Hospital, University of Rome "Sapienza", Viale del Policlinico n.155, 00186, Rome, Italy.

Department of Clinical and Experimental Medicine, "Sapienza", Sant'Andrea Hospital, University of Rome, Via di Grottarossa 1035-1029, 00189, Rome, Italy.

出版信息

Environ Monit Assess. 2020 May 3;192(6):325. doi: 10.1007/s10661-020-08317-y.

DOI:10.1007/s10661-020-08317-y
PMID:32363409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7196178/
Abstract

The recent epidemic of the new SARS-CoV-2 in the northern regions of Italy is putting the organization of the Italian health system under serious attack. The current emergency requires all possible efforts to stem the spread of the virus. In this context, it is clear that we have the urgent need to rely upon etiopathogenetic data, in order to do all possible efforts to block the epidemic. However, observing the trend of the infections in China and the geographic areas of the main outbreaks, it could be hypothesized that air pollution plays a role. In particular, it has been previously demonstrated, in specific populations, a role of particulate matter in worsening clinical presentation of virus infection in airways. Without prejudice to the ascertained virus spread by air droplets or contaminated surfaces, the factors that could have favored its spread remain to be investigated. Moreover, if these observations were to be confirmed, when the health emergency is resolved, it will be mandatory to redesign an economic-productive model in balance with the environment.

摘要

意大利北部地区最近爆发的新型 SARS-CoV-2 疫情正对意大利卫生系统的组织造成严重冲击。当前的紧急情况需要尽一切可能努力阻止病毒的传播。在这种情况下,显然我们迫切需要依靠病因发病数据,尽一切可能努力阻止疫情。然而,观察中国和主要疫情地区的感染趋势,可以假设空气污染起了作用。特别是,之前已经在特定人群中证明了,空气中的颗粒物在恶化呼吸道病毒感染的临床症状方面发挥了作用。在不影响飞沫或受污染表面传播病毒的前提下,仍有待调查有利于其传播的因素。此外,如果这些观察结果得到证实,那么在卫生紧急情况得到解决后,就必须重新设计与环境相平衡的经济生产模式。

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本文引用的文献

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N Engl J Med. 2020 Apr 16;382(16):1564-1567. doi: 10.1056/NEJMc2004973. Epub 2020 Mar 17.
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Sex difference and smoking predisposition in patients with COVID-19.新型冠状病毒肺炎患者的性别差异与吸烟易感性
Lancet Respir Med. 2020 Apr;8(4):e20. doi: 10.1016/S2213-2600(20)30117-X. Epub 2020 Mar 11.
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The transmission and diagnosis of 2019 novel coronavirus infection disease (COVID-19): A Chinese perspective.2019 新型冠状病毒感染疾病(COVID-19)的传播与诊断:中国视角。
J Med Virol. 2020 Jun;92(6):639-644. doi: 10.1002/jmv.25749. Epub 2020 Mar 12.
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Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents.冠状病毒在无生命表面上的持久性及其用杀生物剂灭活。
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