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来自物种的三萜类化合物：植物化学、结构修饰及生物活性

Triterpenoids From Species: Phytochemistry, Structure Modification, and Bioactivities.

作者信息

Wang Pengli, Song Tongxin, Shi Rui, He Mingshuai, Wang Rongrong, Lv Jialin, Jiang Miaomiao

机构信息

Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

出版信息

Front Chem. 2020 Apr 30;8:363. doi: 10.3389/fchem.2020.00363. eCollection 2020.

DOI:10.3389/fchem.2020.00363
PMID:32426329
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7205456/
Abstract

Plants from species belong to the genus of Linn. in family. The tubers of (Sam.) Juzep, also known as in Chinese and in Japanese, have been used in traditional medicine for a long history. Triterpenoids are the main secondary metabolites isolated from species, and reported with various bioactive properties, including anticancer, lipid-regulating, anti-inflammatory, antibacterial, antiviral and diuretic activities. In this brief review, we aimed to summarize the phytochemical and pharmacological characteristics of triterpenoids found in , and discuss their structure modification to enhance cytotoxicity as well.

摘要

来自 科 属 种的植物。（萨姆.）朱泽普的块茎，中文名为 ，日语名为 ，在传统医学中已有很长的使用历史。三萜类化合物是从 种植物中分离出的主要次生代谢产物，并报道具有多种生物活性，包括抗癌、调节脂质、抗炎、抗菌、抗病毒和利尿活性。在这篇简短的综述中，我们旨在总结 中发现的三萜类化合物的植物化学和药理学特征，并讨论它们的结构修饰以增强细胞毒性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/690d/7205456/e4f448a317b9/fchem-08-00363-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/690d/7205456/0245301a6426/fchem-08-00363-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/690d/7205456/c97c72688040/fchem-08-00363-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/690d/7205456/7f173dce27ae/fchem-08-00363-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/690d/7205456/e4f448a317b9/fchem-08-00363-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/690d/7205456/0245301a6426/fchem-08-00363-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/690d/7205456/c97c72688040/fchem-08-00363-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/690d/7205456/7f173dce27ae/fchem-08-00363-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/690d/7205456/e4f448a317b9/fchem-08-00363-g0005.jpg

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