School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, Taiwan.
Department of Leisure and Recreation Management, College of Human Ecology, Taipei City University of Science and Technology, Taipei 11202, Taiwan.
Nutrients. 2020 May 17;12(5):1447. doi: 10.3390/nu12051447.
High-strength or long-duration exercise can lead to significant fatigue, oxidative stress, and muscle damage. The purpose of this study was to examine the effect of mangosteen concentrate drink (MCD) supplementation on antioxidant capacity and lactate clearance in rats after running exercise. Forty rats were divided into five groups: N, non-treatment; C, control; or supplemented with MCD, including M1, M5, and M10 (0.9, 4.5, and 9 mL/day) for 6 weeks. The rats were subjected to 30 min running and exhaustive-running tests using a treadmill. The blood lactate; triglyceride; cholesterol and glucose levels; hepatic and muscular malonaldehyde (MDA) levels; and antioxidant enzymes, including superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT), were analyzed. The results of this study demonstrated that MCD supplementation can increase GPx and CAT activities, alleviate oxidative stress in muscle, and increase lactate clearance, and is thereby beneficial to reduced muscle fatigue after exercise.
高强度或长时间的运动可能导致明显的疲劳、氧化应激和肌肉损伤。本研究旨在探讨山竹浓缩液（MCD）补充对跑步运动后大鼠抗氧化能力和乳酸清除率的影响。将 40 只大鼠分为 5 组：N，未处理；C，对照；或补充 MCD，包括 M1、M5 和 M10（0.9、4.5 和 9 mL/天）6 周。大鼠使用跑步机进行 30 分钟跑步和力竭跑步测试。分析血液乳酸、甘油三酯、胆固醇和血糖水平、肝和肌肉丙二醛（MDA）水平以及超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GPx）和过氧化氢酶（CAT）等抗氧化酶的活性。研究结果表明，MCD 补充可提高 GPx 和 CAT 活性，减轻肌肉氧化应激，增加乳酸清除率，从而有利于运动后减少肌肉疲劳。
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