Department of Chemical Engineering and Center for Soft Matter and Biological Physics, Virginia Tech, Blacksburg, Virgina 24061, United States.
School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
ACS Appl Mater Interfaces. 2020 Aug 5;12(31):34723-34727. doi: 10.1021/acsami.0c11425. Epub 2020 Jul 27.
SARS-CoV-2, the virus that causes the disease COVID-19, remains viable on solids for periods of up to 1 week, so one potential route for human infection is via exposure to an infectious dose from a solid. We have fabricated and tested a coating that is designed to reduce the longevity of SARS-CoV-2 on solids. The coating consists of cuprous oxide (CuO) particles bound with polyurethane. After 1 h on coated glass or stainless steel, the viral titer was reduced by about 99.9% on average compared to the uncoated sample. An advantage of a polyurethane-based coating is that polyurethane is already used to coat a large number of everyday objects. Our coating adheres well to glass and stainless steel as well as everyday items that people may fear to touch during a pandemic, such as a doorknob, a pen, and a credit card keypad button. The coating performs well in the cross-hatch durability test and remains intact and active after 13 days of being immersed in water or after exposure to multiple cycles of exposure to the virus and disinfection.
导致 COVID-19 疾病的 SARS-CoV-2 病毒在固体表面上的存活时间长达 1 周，因此人类感染的一种潜在途径是通过接触固体表面上的传染性剂量。我们已经制造并测试了一种涂层，旨在减少 SARS-CoV-2 在固体表面上的存活时间。该涂层由氧化铜 (CuO) 颗粒与聚氨酯结合而成。在涂有涂层的玻璃或不锈钢上放置 1 小时后，与未涂覆的样品相比，病毒滴度平均降低了约 99.9%。基于聚氨酯的涂层的一个优点是，聚氨酯已经用于涂覆大量日常用品。我们的涂层在玻璃和不锈钢以及人们在大流行期间可能害怕接触的日常物品（如门把手、笔和信用卡键盘按钮）上都有很好的附着力。该涂层在交叉划线耐久性测试中表现良好，在浸入水中 13 天或暴露于多次病毒和消毒循环后仍保持完整和活性。
