Department of Neurosurgery, West China Hospital, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, People's Republic of China.
West China School of Medicine, West China Hospital, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, People's Republic of China.
Jpn J Radiol. 2020 Dec;38(12):1125-1134. doi: 10.1007/s11604-020-01021-4. Epub 2020 Jul 25.
To investigate differences between pituitary adenoma and craniopharyngioma on magnetic resonance imaging (MRI) with image features and three-dimensional texture features.
A total of 126 patients diagnosed with pituitary adenoma (N = 63) or craniopharyngioma (N = 63) were enrolled. Qualitative magnetic resonance (MR) image features and texture features of tumors were extracted from preoperative MRI and evaluated using chi-square test or Mann-Whitney U test. Binary logistic regression analyses were performed to assess their abilities as independent diagnostic predictors, and ROC analyses were conducted to evaluate the diagnostic value of significant features. Mann-Whitney U test and ROC analyses were performed to explore the relationship between MR image features and texture features.
Five MR image features were suggested to be significantly different between pituitary adenoma and craniopharyngioma. Three texture features from contrast-enhanced T1WI (HISTO-Skewness, GLCM-Contrast and GLCM-Energy), two texture features from T2WI (HISTO-Skewness and GLCM-Contrast) showed significant differences between two types of tumors. Logistic regression analyses suggested GLCM-Energy from contrast-enhanced T1WI, HISTO-Skewness and GLCM-Contrast from T2WI could be taken as independent predictors. Moreover, HISTO-Skewness and GLCM-Contrast from T2WI were found to be significantly related to cystic change.
MR image features and texture features were associated with each other, and both types of features represented feasible diagnostic value in discrimination between pituitary adenoma and craniopharyngioma.
通过图像特征和三维纹理特征，研究磁共振成像（MRI）中垂体腺瘤和颅咽管瘤之间的差异。
共纳入 126 例经术前 MRI 诊断为垂体腺瘤（N=63）或颅咽管瘤（N=63）的患者。采用卡方检验或曼-惠特尼 U 检验，从术前 MRI 中提取肿瘤的定性磁共振（MR）图像特征和纹理特征。采用二项逻辑回归分析评估其作为独立诊断预测因子的能力，并进行 ROC 分析评估显著特征的诊断价值。采用曼-惠特尼 U 检验和 ROC 分析，探讨 MR 图像特征与纹理特征之间的关系。
提示垂体腺瘤和颅咽管瘤之间有 5 个 MR 图像特征存在显著差异。增强 T1WI 的 3 个纹理特征（HISTO-Skewness、GLCM-Contrast 和 GLCM-Energy）、T2WI 的 2 个纹理特征（HISTO-Skewness 和 GLCM-Contrast）之间存在显著差异。逻辑回归分析提示，增强 T1WI 的 GLCM-Energy、T2WI 的 HISTO-Skewness 和 GLCM-Contrast 可作为独立预测因子。此外，T2WI 的 HISTO-Skewness 和 GLCM-Contrast 与囊性变显著相关。
MR 图像特征和纹理特征相互关联，两种特征在鉴别垂体腺瘤和颅咽管瘤方面均具有可行的诊断价值。
