健康和腹泻马匹盲肠及大肠的腔内和黏膜微生物群

Arroyo Luis G, Rossi Laura, Santos Bruna P, Gomez Diego E, Surette Michael G, Costa Marcio C

Departments of Clinical Studies, Ontario Veterinary College, University of Guelph, University of Guelph, Guelph, ON N1G 2W1, Canada.

Department of Medicine, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON L8S 4L8, Canada.

Animals (Basel). 2020 Aug 12;10(8):1403. doi: 10.3390/ani10081403.

The aim of this study was to compare the mucosal and luminal content microbiota of the cecum and colon of healthy and diarrheic horses. Marked differences in the richness and in the community composition between the mucosal and luminal microbiota of the cecum and large colon of horses with colitis were observed. Microbial dysbiosis occurs in horses with colitis at different levels of the intestinal tract, and microbiota composition is different between the mucosa and luminal content of diarrheic horses. The changes in some key taxa associated with dysbiosis in the equine intestinal microbiota, such as , and , deserve further inquiry in order to determine their utility for disease diagnosis and treatment.

本研究的目的是比较健康马和腹泻马盲肠及结肠的黏膜和肠腔内容物微生物群。观察到患有结肠炎的马的盲肠和大结肠黏膜与肠腔微生物群在丰富度和群落组成上存在显著差异。患有结肠炎的马在肠道不同水平发生微生物失调，腹泻马的黏膜和肠腔内容物的微生物群组成不同。马肠道微生物群中与失调相关的一些关键分类群的变化，如、和，值得进一步探究，以确定它们在疾病诊断和治疗中的作用。