年龄相关性黄斑变性中的视网膜色素上皮脱离

Karampelas Michael, Malamos Panagiotis, Petrou Petros, Georgalas Ilias, Papaconstantinou Dimitrios, Brouzas Dimitrios

Ophthalmology Department, Hippokration General Hospital, Athens, Greece.

Imaging of the Fundus and Macula, Athens, Greece.

Ophthalmol Ther. 2020 Dec;9(4):739-756. doi: 10.1007/s40123-020-00291-5. Epub 2020 Aug 18.

Retinal pigment epithelial detachment is defined as a separation of the retinal pigment epithelium from the inner collagenous layer of Bruch's membrane. It is a common manifestation in both dry and wet types of age-related macular degeneration. This review aims to provide a comprehensive guide to the pathophysiology, clinical and imaging characteristics, natural course and treatment of the various types of pigment epithelial detachments in order to assist in diagnosis and management of this important feature of age-related macular degeneration.

视网膜色素上皮脱离被定义为视网膜色素上皮与布鲁赫膜的内胶原层分离。它是干性和湿性年龄相关性黄斑变性的常见表现。本综述旨在为各种类型色素上皮脱离的病理生理学、临床和影像学特征、自然病程及治疗提供全面指南，以协助诊断和管理年龄相关性黄斑变性的这一重要特征。