Faris Mo'ez A-Islam E, Salem Mohamed L, Jahrami Haitham A, Madkour Mohamed I, BaHammam Ahmed S
Department of Clinical Nutrition and Dietetics, College of Health Sciences/Research Institute of Medical and Health Sciences (RIMHS), University of Sharjah, Sharjah, United Arab Emirates.
Immunology and Biotechnology Division, Department of Zoology, Faculty of Science, Tanta University, Egypt.
Ann Thorac Med. 2020 Jul-Sep;15(3):125-133. doi: 10.4103/atm.ATM_151_20. Epub 2020 Jun 18.
WITH the growing pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome (SARS)-related coronavirus (SARS-CoV-2) infection, a parallel growing interest arose concerning potential preventive and adjunct therapies, dietary and lifestyle modifications, and remedies that may boost the immunity against SARS-CoV-2 infection. Furthermore, as Ramadan intermittent religious fasting that is practiced by about one and a half billion Muslims throughout the globe is coincide this year with COVID-19 pandemic, a growing debate rose concerning the expected impact of fasting during Ramadan month and the associated dietary and lifestyle behaviors on the body's immunity against the pandemic infection. Published literature was searched to find out how intermittent fasting (IF) and its model of Ramadan affect the various aspects related to the body's immunity against microbial infections. IF was found to impact immunity by changing different related elements, including oxidative stress and inflammation, metabolism, body weight, and body composition. Dietary and lifestyle modifications during Ramadan month and their impact on immunity, such as water intake and hydration status, sleep duration and timing, caloric intake and mealtime, and social and spirtual activities, were addressed. Further research is warranted to figure out how IF during ramadan affects immunity against SARS-CoV-2 infection.
随着由严重急性呼吸综合征（SARS）相关冠状病毒（SARS-CoV-2）感染引起的2019冠状病毒病（COVID-19）大流行的加剧，人们对潜在的预防和辅助治疗、饮食和生活方式的改变以及可能增强对SARS-CoV-2感染免疫力的疗法的兴趣也在同步增加。此外，由于全球约15亿穆斯林所践行的斋月间歇性宗教禁食今年恰逢COVID-19大流行，关于斋月期间禁食以及相关饮食和生活方式行为对身体抵抗大流行感染免疫力的预期影响的争论日益激烈。通过检索已发表的文献，以了解间歇性禁食（IF）及其斋月模式如何影响与身体抵抗微生物感染免疫力相关的各个方面。研究发现，间歇性禁食通过改变不同的相关因素来影响免疫力，这些因素包括氧化应激和炎症、新陈代谢、体重和身体组成。文中还讨论了斋月期间的饮食和生活方式改变及其对免疫力的影响，如水的摄入量和水合状态、睡眠时间和时间安排、热量摄入和用餐时间，以及社交和精神活动。有必要进行进一步的研究，以弄清楚斋月期间的间歇性禁食如何影响对SARS-CoV-2感染的免疫力。
