Dipartimento di Scienze Chimiche e Farmaceutiche, Università degli Studi di Trieste, via Giorgieri 1, 34127 Trieste, Italy.
Biosensors (Basel). 2020 Aug 24;10(9):105. doi: 10.3390/bios10090105.
Phenolic compounds are secondary metabolites frequently found in plants that exhibit many different effects on human health. Because of the relevant bioactivity, their identification and quantification in agro-food matrices as well as in biological samples are a fundamental issue in the field of quality control of food and food supplements, and clinical analysis. In this review, a critical selection of sensors and biosensors for rapid and selective detection of phenolic compounds is discussed. Sensors based on electrochemistry, photoelectrochemistry, fluorescence, and colorimetry are discussed including devices with or without specific recognition elements, such as biomolecules, enzymes and molecularly imprinted materials. Systems that have been tested on real matrices are prevalently considered but also techniques that show potential development in the field.
酚类化合物是植物中常见的次生代谢物，对人类健康有许多不同的影响。由于具有相关的生物活性，因此在农产品食品基质以及生物样品中对其进行鉴定和定量是食品和食品补充剂质量控制以及临床分析领域的一个基本问题。在这篇综述中，我们对用于快速和选择性检测酚类化合物的传感器和生物传感器进行了批判性的选择。讨论了基于电化学、光电化学、荧光和比色法的传感器，包括具有或不具有特定识别元件（如生物分子、酶和分子印迹材料）的器件。本文主要考虑了已经在实际基质上进行测试的系统，但也考虑了在该领域具有潜在发展前景的技术。
