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影响库尔德斯坦省 COVID-19 患者生存的预后因素:2020 年 2 月至 5 月的横断面研究。

The Prognostic Factors Affecting the Survival of Kurdistan Province COVID-19 Patients: A Cross-sectional Study From February to May 2020.

机构信息

Kurdistan University of Medical Sciences, Sanandaj, Iran.

Department of Epidemiology and Biostatistics, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran.

出版信息

Int J Health Policy Manag. 2022 Apr 1;11(4):453-458. doi: 10.34172/ijhpm.2020.155.

Abstract

BACKGROUND

Coronavirus disease 2019 (COVID-19) is a new viral disease and in a short period of time, the world has been affected in various economic, social, and health aspects. This disease has a high rate of transmission and mortality. The aim of this study is to investigate the factors affecting the survival of COVID-19 patients in Kurdistan province.

METHODS

In this retrospective study, the data including demographic features and the patient's clinical background in terms of co-morbidities such as diabetes, cancer, chronic lung disease (CLD), coronary heart disease (CHD), chronic kidney disease (CKD) and weak immune system (WIS) were extracted from electronic medical records. We use Cox's regression proportional hazard (PH) to model.

RESULTS

In this study, out of 1831 patients, 1019 were males (55.7%) and 812 were females (44.3%) with an average age of 52.74 ± 22.16 years. For survival analysis, data from people infected with COVID-19 who died or were still being treated were used. According to Cox's regression analysis, age variables (hazard ratio [HR]: 1.03, CI: 1.02-1.04), patients with a history of diabetes (HR: 2.16, CI: 1.38-3.38), cancer (HR: 3.57, CI: 1.82-7.02), CLD (HR: 2.21, CI: 1.22-4) and CHD (HR: 2.20, CI: 1.57-3.09) were significant and affected the hazard of death in patients with COVID-19 and assuming that the other variables in the model are constant, the hazard of death increases by 3% by increasing one unit (year), and the hazard of death in COVID-19 patients with CHD, diabetes, cancer, CLD is 2.16, 3.57, 2.2 and 2.21, respectively.

CONCLUSION

According to findings, it is necessary to evaluate the prevalence of COVID-19 in patients with CLD, diabetes, cancer, CHD, and elder, as patients with these characteristics may face a greater risk of death. Therefore, we suggest that elders and people with those underlying illnesses need to be under active surveillance and screened frequently.

摘要

背景

2019 年冠状病毒病(COVID-19)是一种新的病毒性疾病,在很短的时间内,世界在经济、社会和健康方面都受到了影响。这种疾病具有很高的传播率和死亡率。本研究旨在探讨影响库尔德斯坦省 COVID-19 患者生存的因素。

方法

在这项回顾性研究中,从电子病历中提取了包括人口统计学特征和患者临床背景在内的数据,这些数据涉及合并症,如糖尿病、癌症、慢性肺病(CLD)、冠心病(CHD)、慢性肾脏病(CKD)和免疫系统较弱(WIS)。我们使用 Cox 的比例风险(PH)回归模型。

结果

在这项研究中,1831 名患者中,1019 名是男性(55.7%),812 名是女性(44.3%),平均年龄为 52.74 ± 22.16 岁。对于生存分析,使用了感染 COVID-19 后死亡或仍在接受治疗的人的数据。根据 Cox 回归分析,年龄变量(风险比[HR]:1.03,CI:1.02-1.04)、有糖尿病史的患者(HR:2.16,CI:1.38-3.38)、癌症(HR:3.57,CI:1.82-7.02)、CLD(HR:2.21,CI:1.22-4)和 CHD(HR:2.20,CI:1.57-3.09)是显著的,并且影响 COVID-19 患者的死亡风险,假设模型中的其他变量保持不变,每增加一个单位(年),死亡风险增加 3%,患有 CHD、糖尿病、癌症、CLD 的 COVID-19 患者的死亡风险分别为 2.16、3.57、2.2 和 2.21。

结论

根据研究结果,有必要评估 CLD、糖尿病、癌症、CHD 和老年人中 COVID-19 的患病率,因为具有这些特征的患者可能面临更大的死亡风险。因此,我们建议老年人和患有这些基础疾病的人需要进行积极监测和频繁筛查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c0b/9309952/d623c78336ec/ijhpm-11-453-g001.jpg

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