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来自沙特阿拉伯生长的新型苯甲酸衍生物及其抗氧化活性。

New benzoic acid derivatives from growing in Saudi Arabia and their antioxidant activity.

作者信息

Al-Haidari Rwaida A, Al-Oqail Mai M

机构信息

Department of Pharmacognosy and Pharmaceutical Chemistry, College of Pharmacy, Taibah University, Al Madinah Al Munawwarah 30078, Saudi Arabia.

Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

出版信息

Saudi Pharm J. 2020 Sep;28(9):1112-1117. doi: 10.1016/j.jsps.2020.07.012. Epub 2020 Aug 3.

Abstract

Two new benzoic acid derivatives: 1--hydroxy benzoyl-3-palmitoyl glycerol () and 6 --hydroxy benzoyl daucosterol (), along with scutellarein-6-methyl ether (), quercetin (), and rutin () had been separated from (Fabaceae) aerial parts from EtOAc fraction. Their characterisation was accomplished by various spectroscopic techniques and by comparing with the published data. The Ethyl acetate (EtOAc) fraction and compounds - had been assessed for their antioxidant potential utilizing DPPH assay. They had significant antioxidant capacities with activity ranged from 19.7 to 95.8%, in comparison to butylated hydroxyanisole (BHA) (93.8%). These findings could provide a further evidence to support the traditional use of for the treatment of chronic or degenerative illnesses.

摘要

从豆科植物[具体植物名称未给出]地上部分的乙酸乙酯萃取物中分离出了两种新的苯甲酸衍生物:1-羟基苯甲酰基-3-棕榈酰甘油([具体编号未给出])和6-羟基苯甲酰基胡萝卜苷([具体编号未给出]),以及黄芩素-6-甲醚([具体编号未给出])、槲皮素([具体编号未给出])和芦丁([具体编号未给出])。通过各种光谱技术并与已发表的数据进行比较完成了它们的表征。利用DPPH法对乙酸乙酯(EtOAc)萃取物及化合物[具体编号未给出]的抗氧化潜力进行了评估。与丁基羟基茴香醚(BHA)(93.8%)相比,它们具有显著的抗氧化能力,活性范围为19.7%至95.8%。这些发现可为支持[具体植物名称未给出]用于治疗慢性或退行性疾病的传统用途提供进一步证据。

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