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饮酒真的与心血管健康有关吗?来自 Kardiovize 2030 项目的证据。

Is Drinking Alcohol Really Linked to Cardiovascular Health? Evidence from the Kardiovize 2030 Project.

机构信息

International Clinical Research Center, St Anne's University Hospital, 65691 Brno, Czech Republic.

Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, 95127 Catania, Italy.

出版信息

Nutrients. 2020 Sep 17;12(9):2848. doi: 10.3390/nu12092848.

DOI:10.3390/nu12092848
PMID:32957567
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7551763/
Abstract

Existing data have described benefits and drawbacks of alcohol consumption on cardiovascular diseases (CVD), but no research has evaluated its association with the cardiovascular health (CVH) score proposed by the American Heart Association. Here, we conducted a cross-sectional analysis on the Kardiovize cohort (Brno, Czech Republic), to investigate the relationship between alcohol consumption and CVH. We included 1773 subjects (aged 25-64 years; 44.2% men) with no history of CVD. We compared CVD risk factors, CVH metrics (i.e., BMI, healthy diet, physical activity level, smoking status, blood pressure, fasting glucose, and total cholesterol) and CVH score between and within several drinking categories. We found that the relationship between drinking habits and CVH was related to the amount of alcohol consumed, drinking patterns, and beverage choices. Heavy drinkers were more likely to smoke tobacco, and to report diastolic blood pressure, fasting glucose, triglycerides, and low-density lipoprotein (LDL)-cholesterol at higher level than non-drinkers. Among drinkers, however, people who exclusively drank wine exhibited better CVH than those who exclusively drank beer. Although our findings supported the hypothesis that drinking alcohol was related to the CVH in general, further prospective research is needed to understand whether the assessment of CVH should incorporate information on alcohol consumption.

摘要

现有数据描述了饮酒对心血管疾病 (CVD) 的益处和弊端,但尚无研究评估其与美国心脏协会提出的心血管健康 (CVH) 评分的关系。在这里,我们对 Kardiovize 队列(捷克共和国布尔诺)进行了横断面分析,以研究饮酒与 CVH 之间的关系。我们纳入了 1773 名无 CVD 病史的受试者(年龄 25-64 岁;44.2%为男性)。我们比较了不同饮酒类别之间和之内的 CVD 危险因素、CVH 指标(即 BMI、健康饮食、身体活动水平、吸烟状况、血压、空腹血糖和总胆固醇)和 CVH 评分。我们发现,饮酒习惯与 CVH 之间的关系与饮酒量、饮酒模式和饮料选择有关。重度饮酒者更有可能吸烟,并且报告的舒张压、空腹血糖、甘油三酯和低密度脂蛋白(LDL)-胆固醇水平高于非饮酒者。然而,在饮酒者中,只喝葡萄酒的人比只喝啤酒的人 CVH 更好。尽管我们的研究结果支持饮酒与总体 CVH 相关的假设,但仍需要进一步的前瞻性研究来了解 CVH 的评估是否应纳入饮酒信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d8/7551763/4f73218e0bb9/nutrients-12-02848-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d8/7551763/e1ac3772ff1d/nutrients-12-02848-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d8/7551763/ddf06a1dea8f/nutrients-12-02848-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d8/7551763/554ce6f3038b/nutrients-12-02848-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d8/7551763/4f73218e0bb9/nutrients-12-02848-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d8/7551763/e1ac3772ff1d/nutrients-12-02848-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d8/7551763/ddf06a1dea8f/nutrients-12-02848-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d8/7551763/554ce6f3038b/nutrients-12-02848-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d8/7551763/4f73218e0bb9/nutrients-12-02848-g004.jpg

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