Ogunmoroti Oluseye, Osibogun Olatokunbo, McClelland Robyn L, Burke Gregory L, Nasir Khurram, Michos Erin D
The Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Baltimore, Maryland.
Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, Florida.
Clin Cardiol. 2019 Jan;42(1):151-158. doi: 10.1002/clc.23125. Epub 2018 Dec 17.
Alcohol consumption is associated with cardiovascular disease (CVD), with moderate drinkers having decreased CVD risk compared to non- and heavy drinkers. However, whether alcohol consumption is associated with ideal cardiovascular health (CVH), assessed by the American Heart Association's (AHA) Life's Simple 7 (LS7) metrics, and whether associations differ by sex, is uncertain.
Heavy alcohol consumption is associated with worse CVH.
We explored associations between alcohol consumption and CVH in a multi-ethnic population including 6506 participants free of CVD, aged 45 to 84 years. Each LS7 metric was scored 0 to 2 points. Total score was categorized as inadequate (0-8), average (9-10) and optimal (11-14). Participants were classified as never, former or current drinkers. Current drinkers were categorized as <1 (light), 1 to 2 (moderate) and >2 (heavy) drinks/day. Multinomial logistic regression models assessed associations between alcohol and CVH, adjusted for age, sex, race/ethnicity, education, income, and health insurance.
Mean (SD) age was 62 (10) years, 53% were women. Compared to never drinkers, those with >2 drinks/day were less likely to have average [0.61 (0.43-0.87)] and optimal CVH [0.29 (0.17-0.49)]. Binge drinking was also associated with unfavorable CVH. Overall, there was no independent association for light or moderate drinking with CVH. However, women with 1 to 2 drinks/day were more likely to have optimal CVH [1.85 (1.19-2.88)] compared to non-drinking women, which was not seen in men.
Heavy alcohol consumption was associated with unfavorable CVH. Although light or moderate drinking may be associated with a more favorable CVH in women, overall, the association was not strong.
饮酒与心血管疾病(CVD)相关,与不饮酒者和重度饮酒者相比,适度饮酒者患心血管疾病的风险降低。然而,饮酒是否与理想心血管健康(CVH)相关(通过美国心脏协会(AHA)的“生命简单7项指标”(LS7)进行评估),以及这种关联是否因性别而异,尚不确定。
重度饮酒与较差的CVH相关。
我们在一个多民族人群中探讨了饮酒与CVH之间的关联,该人群包括6506名年龄在45至84岁之间且无CVD的参与者。每项LS7指标的得分范围为0至2分。总得分分为不足(0 - 8分)、平均(9 - 10分)和最佳(11 - 14分)。参与者被分为从不饮酒者、既往饮酒者或当前饮酒者。当前饮酒者被分为每天饮酒<1杯(轻度)、1至2杯(中度)和>2杯(重度)。多项逻辑回归模型评估了饮酒与CVH之间的关联,并对年龄、性别、种族/民族、教育程度、收入和医疗保险进行了调整。
平均(标准差)年龄为62(10)岁,53%为女性。与从不饮酒者相比,每天饮酒>2杯的人具有平均CVH[0.61(0.43 - 0.87)]和最佳CVH[0.29(0.17 - 0.49)]的可能性较小。暴饮也与不良的CVH相关。总体而言,轻度或适度饮酒与CVH之间没有独立关联。然而,与不饮酒的女性相比,每天饮酒1至2杯的女性更有可能具有最佳CVH[1.85(1.19 - 2.88)],而男性中未观察到这种情况。
重度饮酒与不良的CVH相关。虽然轻度或适度饮酒可能与女性更有利的CVH相关,但总体而言,这种关联并不强烈。