Jarvis W R, Olson D, Tablan O, Martone W J
Hospital Infections Program, Center for Infectious Diseases, Atlanta, GA 30333.
Eur J Epidemiol. 1987 Sep;3(3):233-6. doi: 10.1007/BF00149729.
Pseudomonas cepacia has recently emerged as an important nosocomial pathogen. We analyzed a national nosocomial infections database, the National Nosocomial Infections Surveillance (NNIS) system, to describe the epidemiology of endemic nosocomial P. cepacia infections. Between 1980 and 1985, the P. cepacia nosocomial infection rate was 2.4 per 100,000 patient discharges. During this period, there was a significant increase in the P. cepacia infection rate. The highest infection rate was reported from large medical school-affiliated hospitals. Over 90% of the infections were reported from medicine and surgery services. The most frequently reported site of infection was the lower respiratory tract (31%), followed by blood (20%) and the urinary tract (20%). Nosocomial P. cepacia infections are often associated with mortality, particularly when they involve the lung. These data confirm the hypothesis that P. cepacia is an emerging nosocomial pathogen and suggest that the epidemiology of endemic infections differs from that reported for epidemic infections.
洋葱伯克霍尔德菌最近已成为一种重要的医院病原体。我们分析了一个全国医院感染数据库——国家医院感染监测（NNIS）系统，以描述地方性医院洋葱伯克霍尔德菌感染的流行病学特征。1980年至1985年间，洋葱伯克霍尔德菌医院感染率为每10万例出院患者中有2.4例。在此期间，洋葱伯克霍尔德菌感染率显著上升。大型医学院附属医院报告的感染率最高。超过90%的感染报告来自内科和外科服务科室。最常报告的感染部位是下呼吸道（31%），其次是血液（20%）和泌尿道（20%）。医院洋葱伯克霍尔德菌感染常与死亡率相关，尤其是当感染累及肺部时。这些数据证实了洋葱伯克霍尔德菌是一种新兴医院病原体的假设，并表明地方性感染的流行病学特征与报告的流行性感染不同。
