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新型纳米结构碳涂层可抑制细菌生长,但对动物细胞无影响。

New Nanostructured Carbon Coating Inhibits Bacterial Growth, but Does Not Influence on Animal Cells.

作者信息

Barkhudarov Eduard M, Kossyi Igor A, Anpilov Andrey M, Ivashkin Petr I, Artem'ev Konstantin V, Moryakov Igor V, Misakyan Mamikon A, Christofi Nick, Burmistrov Dmitry E, Smirnova Veronika V, Ivanyuk Veronika V, Bunkin Nikolay F, Kozlov Valery A, Penkov Nikita V, Sharapov Mars G, Volkov Mikhail Yu, Sevostyanov Mikhail A, Lisitsyn Andrey B, Semenova Anastasia A, Rebezov Maksim B, Gudkov Sergey V

机构信息

Prokhorov General Physics Institute of the Russian Academy of Sciences, 119991 Moscow, Russia.

Higher School of Economics, National Research University, 101000 Moscow, Russia.

出版信息

Nanomaterials (Basel). 2020 Oct 27;10(11):2130. doi: 10.3390/nano10112130.

DOI:10.3390/nano10112130
PMID:33120890
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7692575/
Abstract

An electrospark technology has been developed for obtaining a colloidal solution containing nanosized amorphous carbon. The advantages of the technology are its low cost and high performance. The colloidal solution of nanosized carbon is highly stable. The coatings on its basis are nanostructured. They are characterized by high adhesion and hydrophobicity. It was found that the propagation of microorganisms on nanosized carbon coatings is significantly hindered. At the same time, eukaryotic animal cells grow and develop on nanosized carbon coatings, as well as on the nitinol medical alloy. The use of a colloidal solution as available, cheap and non-toxic nanomaterial for the creation of antibacterial coatings to prevent biofilm formation seems to be very promising for modern medicine, pharmaceutical and food industries.

摘要

一种用于获得含有纳米尺寸非晶碳的胶体溶液的电火花技术已经被开发出来。该技术的优点是成本低且性能高。纳米尺寸碳的胶体溶液高度稳定。基于它的涂层是纳米结构的。它们具有高附着力和疏水性的特点。研究发现,微生物在纳米尺寸碳涂层上的繁殖受到显著阻碍。同时,真核动物细胞在纳米尺寸碳涂层上以及在镍钛诺医用合金上生长和发育。将这种胶体溶液用作一种可得、廉价且无毒的纳米材料来制造抗菌涂层以防止生物膜形成,对于现代医学、制药和食品工业而言似乎非常有前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/03209dbcb222/nanomaterials-10-02130-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/c74e6726f27b/nanomaterials-10-02130-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/6e8f6ce0bf7c/nanomaterials-10-02130-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/5b2832433065/nanomaterials-10-02130-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/69f5eadab7be/nanomaterials-10-02130-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/025822488acb/nanomaterials-10-02130-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/443df15a18d3/nanomaterials-10-02130-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/69c0ea729e41/nanomaterials-10-02130-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/03209dbcb222/nanomaterials-10-02130-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/c74e6726f27b/nanomaterials-10-02130-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/6e8f6ce0bf7c/nanomaterials-10-02130-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/5b2832433065/nanomaterials-10-02130-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/69f5eadab7be/nanomaterials-10-02130-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/025822488acb/nanomaterials-10-02130-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/443df15a18d3/nanomaterials-10-02130-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/69c0ea729e41/nanomaterials-10-02130-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9c0/7692575/03209dbcb222/nanomaterials-10-02130-g008.jpg

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