Mohammadi Leila, Behnam Hamid, Tavakkoli Jahan, Avanaki Kamran
Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Department of Biomedical Engineering, Iran University of Science and Technology, Tehran 1684613114, Iran.
Biomed Opt Express. 2020 Sep 14;11(10):5542-5556. doi: 10.1364/BOE.402027. eCollection 2020 Oct 1.
Skull bone represents a highly acoustical impedance mismatch and a dispersive barrier for the propagation of acoustic waves. Skull distorts the amplitude and phase information of the received waves at different frequencies in a transcranial brain imaging. We study a novel algorithm based on vector space similarity model for the compensation of the skull-induced distortions in transcranial photoacoustic microscopy. The results of the algorithm tested on a simplified numerical skull phantom, demonstrate a fully recovered vasculature with the recovery rate of 91.9%.
颅骨代表了一个高度的声阻抗失配以及声波传播的色散屏障。在经颅脑成像中，颅骨会扭曲不同频率下接收波的幅度和相位信息。我们研究了一种基于向量空间相似性模型的新算法，用于补偿经颅光声显微镜中颅骨引起的失真。在一个简化的数值颅骨模型上测试该算法的结果表明，血管系统完全恢复，恢复率为91.9%。
