多语言社区中临床研究的教育水平与知情同意书的首选语言

Level of education and preferred language of informed consent for clinical research in a multi-lingual community.

作者信息

Muzanyi Grace, Sekitoleko Isaac, Johnson John L, Lunkuse Jane, Nalugwa Gladys, Nassali Joanita, Mafigiri David Kaawa

机构信息

Uganda-Case Western Reserve University Research Collaboration, Kampala, Uganda.

Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

出版信息

Afr Health Sci. 2020 Jun;20(2):955-959. doi: 10.4314/ahs.v20i2.51.

DOI:10.4314/ahs.v20i2.51

PMID:33163064

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7609127/

Abstract

BACKGROUND

Low education levels and language barriers present challenges in obtaining informed consent for clinical research.

OBJECTIVE

To describe and correlate the association between the level of education and the participant's preferred language of consent.

DESIGN

Descriptive-analytical cross-sectional study.

PARTICIPANTS

Adults being consented for participation in tuberculosis(TB) research studies in an East African community with varying levels of education.

PROCEDURES

We analyzed data on demographic and educational characteristics collected from adults being consented for participation in TB studies .Only participants who could understand and speak Luganda (the main local language) or English (the official language of Uganda) were included in this analysis.

RESULTS

A total of 523 participants were consented between April 2015 and December 2017 and included in this analysis; 250 below Senior four (< 11yrs of education), 114 senior four (at 11yrs of education),73 senior five-senior six (12-13yrs of education) and 86 beyond senior six (> 13yrs of education). We noted that the preference for English rises with the rising levels of education and peaked at beyond senior six (83%Vs17%,OR=49,95%CI:22.8-106.3,p<0.001).Participants below senior four preferred Luganda Vs senior four and above(OR=16.9,95%CI:9.9-28.8,p<0.001).

CONCLUSION

Rising education levels of participants were associated with preference for English language usage during initial consent for clinical research studies.

摘要

背景

低教育水平和语言障碍给临床研究获得知情同意带来了挑战。

目的

描述并关联教育水平与参与者首选的同意语言之间的关系。

设计

描述性分析横断面研究。

参与者

在东非一个教育水平各异的社区中，同意参与结核病（TB）研究的成年人。

程序

我们分析了从同意参与TB研究的成年人中收集的人口统计学和教育特征数据。本分析仅纳入了能够理解并说卢干达语（当地主要语言）或英语（乌干达官方语言）的参与者。

结果

2015年4月至2017年12月期间，共有523名参与者同意参与并纳入本分析；其中250人低于高四年级（教育年限<11年），114人是高四年级（教育年限为11年），73人是高五至高六年级（教育年限为12 - 13年），86人高于高六年级（教育年限>13年）。我们注意到，对英语的偏好随着教育水平的提高而上升，并在高于高六年级时达到峰值（83%对17%，OR = 49，95%CI：22.8 - 106.3，p<0.001）。低于高四年级的参与者比高四年级及以上的参与者更喜欢卢干达语（OR = 16.9，95%CI：9.9 - 28.8，p<0.001）。