Kahase Daniel, Haile Kassahun
Department of Medical Laboratory Science, College of Medicine and Health Science, Wolkite University, Wolkite, Ethiopia.
Res Rep Trop Med. 2020 Nov 19;11:141-147. doi: 10.2147/RRTM.S282557. eCollection 2020.
Globally, infection affects approximately 4.4 billion people. The burden of the infection varies within and between countries, with a higher prevalence reported from developing countries including Ethiopia. Thus, this study aimed to determine the magnitude and predictors of infection among dyspeptic patients who visited Wachemo University Nigist Eleni Mohammed Memorial Referral Hospital, Southwest Ethiopia.
Consecutive willing dyspeptic adult patients (n=405) were enrolled in a cross-sectional study done from September to December 18, 2019. Socio-demographic and behavioral characteristics of the study participants were gathered by a pretested structured questionnaire. Stool samples were examined for antigens using Wondfo one step feces test kit. SPSS version 20 was utilized to compute descriptive statistics, binary and multivariate logistic regression. A p-value of <0.05 was considered statistically significant.
Mean age of patients was 30 (± 7.4 SD) years, and 56.8% of participants were females. About 51.4% (208/405) of adult dyspeptic patients were infected with . Being female gender (AOR꞊ 2.56, CI 95% ꞊1.61-4.07, p꞊0.001), consumption of alcohol (AOR꞊1.95, CI 95% ꞊1.02-3.73, p꞊ 0.019) and being undernourished (underweighted) (AOR꞊ 4.59, CI 95%꞊ 1.28-16.45, p꞊0.019) were independent predictors of infection.
In the study area, high (51.4%) magnitude of infection was observed in dyspeptic patients and significantly associated with female gender, alcohol consumption, and undernourishment.
在全球范围内,感染影响着约44亿人。感染负担在不同国家内部和国家之间存在差异,包括埃塞俄比亚在内的发展中国家报告的感染率较高。因此,本研究旨在确定到访埃塞俄比亚西南部瓦切莫大学尼吉斯特·埃莱尼·穆罕默德纪念转诊医院的消化不良患者中感染的严重程度及预测因素。
2019年9月至12月18日,对连续入选的有意愿的成年消化不良患者(n = 405)进行了一项横断面研究。通过预先测试的结构化问卷收集研究参与者的社会人口学和行为特征。使用万孚一步粪便检测试剂盒检测粪便样本中的抗原。采用SPSS 20版计算描述性统计量、二元和多变量逻辑回归。p值<0.05被认为具有统计学意义。
患者的平均年龄为30(±7.4标准差)岁,56.8%的参与者为女性。约51.4%(208/405)的成年消化不良患者感染了[此处原文缺失感染病原体名称]。女性(调整后比值比[AOR]:2.56,95%置信区间[CI]:1.61 - 4.07,p = 0.001)、饮酒(AOR:1.95,95% CI:1.02 - 3.73,p = 0.019)和营养不良(体重过轻)(AOR:4.59,95% CI:1.28 - 16.45,p = 0.019)是感染[此处原文缺失感染病原体名称]的独立预测因素。
在研究区域,消化不良患者中观察到较高的[此处原文缺失感染病原体名称]感染率(51.4%),且与女性性别、饮酒和营养不良显著相关。