Postgraduate Program in Dentistry, School of Dentistry, University of Pernambuco Av. General. Newton Cavalcanti, 1650 - Tabatinga Camaragibe, Zip code: 54756-220, Recife/PE, Brazil
Med Oral Patol Oral Cir Bucal. 2021 Jan 1;26(1):e108-e113. doi: 10.4317/medoral.24056.
Benign tumors of the salivary glands are a group of lesions with varied histopathological and clinical spectrum. The aim was to determine the incidence and clinicopathological characteristics of benign salivary gland neoplasms diagnosed between 2007 and 2016 in a single center located in northeastern Brazil.
Records regarding sex, age, anatomical location, histopathological subtype and treatment were retrieved, and data were analyzed using the Stata/IC software (version 12.0).
There were above 7,100 cases of neoplasms in the head and neck region, of which 403 corresponded to salivary gland neoplasms. Of these, 238 (59%) were benign, being pleomorphic adenoma (PA) the most frequent neoplasm (n=178; 74.8%), followed by Warthin's tumor (WT) (n=23; 9.7%). Overall, most cases occurred in females (n=136; 57.1%) and age ranged from 11 to 83 years. The parotid gland (n=188; 79%) was the most common anatomical site, and all patients were treated by surgical excision. Of the cases diagnosed as PA, malignant transformation to carcinoma ex-pleomorphic adenoma (CAEXPA) occurred in 7 (3.9%) cases.
The present study confirmed the clinical and demographic profile of benign salivary gland neoplasms, which contributes to the continuous knowledge of current data about these lesions.
唾液腺良性肿瘤是一组具有多种组织病理学和临床特征的病变。本研究旨在确定 2007 年至 2016 年期间在巴西东北部的一个单一中心诊断的良性唾液腺肿瘤的发病率和临床病理特征。
检索了性别、年龄、解剖部位、组织病理学亚型和治疗的记录，并使用 Stata/IC 软件（版本 12.0）进行数据分析。
头颈部有超过 7100 例肿瘤，其中 403 例为唾液腺肿瘤。这些肿瘤中，238 例（59%）为良性，多形性腺瘤（PA）最常见（n=178；74.8%），其次是沃辛瘤（WT）（n=23；9.7%）。总体而言，大多数病例发生在女性（n=136；57.1%），年龄在 11 至 83 岁之间。最常见的解剖部位是腮腺（n=188；79%），所有患者均接受手术切除。在诊断为 PA 的病例中，有 7 例（3.9%）发生癌在多形性腺瘤（CAEXPA）恶变。
本研究证实了良性唾液腺肿瘤的临床和人口统计学特征，有助于不断了解这些病变的现有数据。
