视网膜静脉阻塞患者血小板与淋巴细胞比值的评估
Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion.
作者信息
Kurtul Bengi Ece, Çakmak Ayșe İdil, Elbeyli Ahmet, Özarslan Özcan Deniz, Özcan Sait Coșkun, Cankurtaran Veysel
机构信息
Department of Ophthalmology, Tayfur Ata Sökmen Faculty of Medicine, Hatay Mustafa Kemal University, 31060, Alahan, Hatay, Turkey.
Department of Ophthalmology, Tayfur Ata Sökmen Faculty of Medicine, Hatay Mustafa Kemal University, Hatay, Turkey.
出版信息
Ther Adv Ophthalmol. 2020 Nov 18;12:2515841420971949. doi: 10.1177/2515841420971949. eCollection 2020 Jan-Dec.
PURPOSE
To investigate platelet-to-lymphocyte ratio (PLR) in retinal vein occlusion (RVO) patients.
METHODS
In this study, we retrospectively reviewed data of 32 patients with RVO (RVO group) and 32 age- and sex-matched participants without RVO (control group) between January 2017 and March 2019. The PLR was determined by dividing the platelet count by the lymphocyte count.
RESULTS
Age and gender were comparable between the groups ( = 0.204 and = 0.800, respectively). PLR was significantly elevated in the RVO group compared with the control group (137 (113-164) vs 101 (86-129), = 0.001)). In the receiver operator characteristics curve analysis, the optimal cut-off value of PLR for predicting RVO was 123, with 69% sensitivity and 72% specificity.
CONCLUSION
We report that PLR are elevated in RVO, suggesting that PLR may be a useful marker for RVO.
目的
研究视网膜静脉阻塞（RVO）患者的血小板与淋巴细胞比值（PLR）。
方法
在本研究中，我们回顾性分析了2017年1月至2019年3月期间32例RVO患者（RVO组）和32例年龄及性别匹配的无RVO参与者（对照组）的数据。PLR通过血小板计数除以淋巴细胞计数来确定。
结果
两组之间的年龄和性别具有可比性（分别为=0.204和=0.800）。与对照组相比，RVO组的PLR显著升高（137（113 - 164）对101（86 - 129），=0.001）。在受试者工作特征曲线分析中，预测RVO的PLR最佳截断值为123，敏感性为69%，特异性为72%。
结论
我们报告RVO患者的PLR升高，提示PLR可能是RVO的一个有用标志物。
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