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视网膜静脉阻塞患者血小板与淋巴细胞比值的评估

Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion.

作者信息

Kurtul Bengi Ece, Çakmak Ayșe İdil, Elbeyli Ahmet, Özarslan Özcan Deniz, Özcan Sait Coșkun, Cankurtaran Veysel

机构信息

Department of Ophthalmology, Tayfur Ata Sökmen Faculty of Medicine, Hatay Mustafa Kemal University, 31060, Alahan, Hatay, Turkey.

Department of Ophthalmology, Tayfur Ata Sökmen Faculty of Medicine, Hatay Mustafa Kemal University, Hatay, Turkey.

出版信息

Ther Adv Ophthalmol. 2020 Nov 18;12:2515841420971949. doi: 10.1177/2515841420971949. eCollection 2020 Jan-Dec.

DOI:10.1177/2515841420971949
PMID:33283155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7686591/
Abstract

PURPOSE

To investigate platelet-to-lymphocyte ratio (PLR) in retinal vein occlusion (RVO) patients.

METHODS

In this study, we retrospectively reviewed data of 32 patients with RVO (RVO group) and 32 age- and sex-matched participants without RVO (control group) between January 2017 and March 2019. The PLR was determined by dividing the platelet count by the lymphocyte count.

RESULTS

Age and gender were comparable between the groups ( = 0.204 and  = 0.800, respectively). PLR was significantly elevated in the RVO group compared with the control group (137 (113-164) vs 101 (86-129),  = 0.001)). In the receiver operator characteristics curve analysis, the optimal cut-off value of PLR for predicting RVO was 123, with 69% sensitivity and 72% specificity.

CONCLUSION

We report that PLR are elevated in RVO, suggesting that PLR may be a useful marker for RVO.

摘要

目的

研究视网膜静脉阻塞(RVO)患者的血小板与淋巴细胞比值(PLR)。

方法

在本研究中,我们回顾性分析了2017年1月至2019年3月期间32例RVO患者(RVO组)和32例年龄及性别匹配的无RVO参与者(对照组)的数据。PLR通过血小板计数除以淋巴细胞计数来确定。

结果

两组之间的年龄和性别具有可比性(分别为=0.204和=0.800)。与对照组相比,RVO组的PLR显著升高(137(113 - 164)对101(86 - 129),=0.001)。在受试者工作特征曲线分析中,预测RVO的PLR最佳截断值为123,敏感性为69%,特异性为72%。

结论

我们报告RVO患者的PLR升高,提示PLR可能是RVO的一个有用标志物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e6/7686591/47511017663d/10.1177_2515841420971949-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e6/7686591/3a06fe32d6f0/10.1177_2515841420971949-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e6/7686591/47511017663d/10.1177_2515841420971949-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e6/7686591/3a06fe32d6f0/10.1177_2515841420971949-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e6/7686591/47511017663d/10.1177_2515841420971949-fig2.jpg

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本文引用的文献

1
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2
A 12-month, multicenter, parallel group comparison of dexamethasone intravitreal implant versus ranibizumab in branch retinal vein occlusion.地塞米松玻璃体内植入物与雷珠单抗治疗视网膜分支静脉阻塞的12个月多中心平行组比较
Eur J Ophthalmol. 2018 Nov;28(6):697-705. doi: 10.1177/1120672117750058. Epub 2018 Apr 9.
3
Assessment of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Patients with Dry Eye Disease.
在无风险因素的患者中,全身免疫炎症指数与无并发症的超声乳化白内障吸除术后假性囊膜下黄斑水肿有关。
BMC Ophthalmol. 2022 Sep 21;22(1):378. doi: 10.1186/s12886-022-02606-5.
4
Platelet-Derived Procoagulant Microvesicles Are Elevated in Patients with Retinal Vein Occlusion (RVO).血小板衍生促凝微泡在视网膜静脉阻塞(RVO)患者中升高。
J Clin Med. 2022 Aug 30;11(17):5099. doi: 10.3390/jcm11175099.
5
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6
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J Clin Med. 2021 Jul 12;10(14):3080. doi: 10.3390/jcm10143080.
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6
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7
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Eur Rev Med Pharmacol Sci. 2016 May;20(10):1934-9.
8
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Cardiorenal Med. 2015 Apr;5(2):96-104. doi: 10.1159/000371496. Epub 2015 Feb 7.
10
Association of neutrophil/lymphocyte ratio and retinal vein occlusion.中性粒细胞/淋巴细胞比值与视网膜静脉阻塞的关联。
Eur J Ophthalmol. 2015 Jul-Aug;25(4):343-6. doi: 10.5301/ejo.5000570. Epub 2015 Jan 27.