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利用基于代理的模型探索 COVID-19 接触者追踪应用程序的有效性。

Exploring the effectiveness of a COVID-19 contact tracing app using an agent-based model.

机构信息

MRC/CSO University of Glasgow, Social and Public Health Science Unit, Berkeley Square, 99 Berkeley Street, Glasgow, G3 7HR, Scotland.

出版信息

Sci Rep. 2020 Dec 17;10(1):22235. doi: 10.1038/s41598-020-79000-y.

Abstract

A contact-tracing strategy has been deemed necessary to contain the spread of COVID-19 following the relaxation of lockdown measures. Using an agent-based model, we explore one of the technology-based strategies proposed, a contact-tracing smartphone app. The model simulates the spread of COVID-19 in a population of agents on an urban scale. Agents are heterogeneous in their characteristics and are linked in a multi-layered network representing the social structure-including households, friendships, employment and schools. We explore the interplay of various adoption rates of the contact-tracing app, different levels of testing capacity, and behavioural factors to assess the impact on the epidemic. Results suggest that a contact tracing app can contribute substantially to reducing infection rates in the population when accompanied by a sufficient testing capacity or when the testing policy prioritises symptomatic cases. As user rate increases, prevalence of infection decreases. With that, when symptomatic cases are not prioritised for testing, a high rate of app users can generate an extensive increase in the demand for testing, which, if not met with adequate supply, may render the app counterproductive. This points to the crucial role of an efficient testing policy and the necessity to upscale testing capacity.

摘要

在放宽封锁措施后,接触者追踪策略被认为是控制 COVID-19 传播的必要手段。我们使用基于代理的模型探索了所提出的基于技术的策略之一,即接触者追踪智能手机应用程序。该模型模拟了城市规模的人群中 COVID-19 的传播。代理在其特征上是异构的,并通过代表社会结构的多层网络链接在一起,包括家庭、友谊、就业和学校。我们探讨了接触者追踪应用程序的各种采用率、不同水平的检测能力以及行为因素的相互作用,以评估其对疫情的影响。结果表明,当接触者追踪应用程序伴随着足够的检测能力或当检测政策优先考虑有症状的病例时,它可以大大降低人群中的感染率。随着用户率的增加,感染的流行率会降低。如果不优先对有症状的病例进行检测,那么大量的应用程序用户可能会导致对检测的需求大量增加,如果不能满足足够的供应,可能会使应用程序适得其反。这表明有效的检测政策和扩大检测能力的必要性至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f329/7746740/6647a087c83b/41598_2020_79000_Fig1_HTML.jpg

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