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评价正畸治疗中镍和钛的释放。

Evaluation of the release of nickel and titanium under orthodontic treatment.

机构信息

Facultad de Odontología, Universidad Autónoma del Estado de México, Av. Paseo Tollocan esq. Jesús Carranza. Colonia Universidad, C. P. 50130, Toluca de Lerdo, Mexico.

Centro de Investigación en Química Sustentable, CIQS, UAEM-UNAM, Universidad Autónoma del Estado de México, Carretera Km. 14.5, Unidad San Cayetano, Toluca-Atlacomulco, C. P. 50200, Toluca de Lerdo, México.

出版信息

Sci Rep. 2020 Dec 17;10(1):22280. doi: 10.1038/s41598-020-79221-1.

DOI:10.1038/s41598-020-79221-1
PMID:33335223
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7747632/
Abstract

The metal alloys used in dentistry are made mainly of nickel (Ni), titanium (Ti), and other elements such as molybdenum (Mo), zirconium (Zr), iron (Fe), tin (Sn), chrome (Cr), carbon (C), copper (Cu) and niobium (Nb) which can release metal ions in unstable environments. The aim of this work was determine the salivary pH before and during orthodontic treatment; evaluate the release of metal ions, mainly Ni and Ti, in urine and saliva using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES); and evaluate the corrosion using Scanning Electronic Microscopy (SEM). In this study, we selected 35 individuals under orthodontic treatment, from whom saliva and urine samples were collected in 3 stages: (a) basal, (b) at 3 and (c) 6 months after the placement of the fixed appliances. SEM analyzed the Ni-Ti (0.016″) and stainless steel (SS) (0.016 × 0.022″) archs after 1 month of being in contact with the oral cavity. Statistical analysis was performed with Stata using the ANOVA model of repeated measures with a p < 0.05. A statistically significant difference in the concentration of Ni in saliva were found between 3 and 6 months of intervention and Ti in urine was found 3 and 6 months.

摘要

牙科中使用的金属合金主要由镍 (Ni)、钛 (Ti) 和其他元素组成，如钼 (Mo)、锆 (Zr)、铁 (Fe)、锡 (Sn)、铬 (Cr)、碳 (C)、铜 (Cu) 和铌 (Nb)，它们在不稳定的环境中会释放出金属离子。本工作旨在：确定正畸治疗前后唾液的 pH 值；使用电感耦合等离子体发射光谱法 (ICP-OES) 评估尿液和唾液中主要为 Ni 和 Ti 的金属离子释放情况；使用扫描电子显微镜 (SEM) 评估腐蚀情况。在这项研究中，我们选择了 35 名正在接受正畸治疗的个体，从他们那里收集了唾液和尿液样本，分为 3 个阶段：(a) 基础期，(b) 固定矫治器放置后 3 个月，(c) 6 个月。在与口腔接触 1 个月后，SEM 分析了 Ni-Ti（0.016″）和不锈钢（SS）（0.016×0.022″）弓丝。使用 Stata 软件进行统计分析，采用重复测量方差分析模型，p<0.05 为差异有统计学意义。在干预 3 至 6 个月期间，唾液中 Ni 的浓度和尿液中 Ti 的浓度均存在统计学差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd2/7747632/bf236e30201d/41598_2020_79221_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd2/7747632/b5baae0fa9e8/41598_2020_79221_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd2/7747632/b3c4d544ed19/41598_2020_79221_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd2/7747632/8c77db215760/41598_2020_79221_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd2/7747632/bf236e30201d/41598_2020_79221_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd2/7747632/b5baae0fa9e8/41598_2020_79221_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd2/7747632/b3c4d544ed19/41598_2020_79221_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd2/7747632/8c77db215760/41598_2020_79221_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd2/7747632/bf236e30201d/41598_2020_79221_Fig4_HTML.jpg

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Am J Orthod Dentofacial Orthop. 2021 Jul;160(1):101-112. doi: 10.1016/j.ajodo.2020.03.035. Epub 2021 May 7.
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