Department of Computing Science, University of Aberdeen, AB24 3UE, Aberdeen, UK.
Department of Computing Science, University of Aberdeen, AB24 3UE, Aberdeen, UK.
Comput Biol Med. 2021 Mar;130:104181. doi: 10.1016/j.compbiomed.2020.104181. Epub 2020 Dec 22.
Deep learning methods have already enjoyed an unprecedented success in medical imaging problems. Similar success has been evidenced when it comes to the detection of COVID-19 from medical images, therefore deep learning approaches are considered good candidates for detecting this disease, in collaboration with radiologists and/or physicians. In this paper, we propose a new approach to detect COVID-19 via exploiting a conditional generative adversarial network to generate synthetic images for augmenting the limited amount of data available. Additionally, we propose two deep learning models following a lightweight architecture, commensurating with the overall amount of data available. Our experiments focused on both binary classification for COVID-19 vs Normal cases and multi-classification that includes a third class for bacterial pneumonia. Our models achieved a competitive performance compared to other studies in literature and also a ResNet8 model. Our best performing binary model achieved 98.7% accuracy, 100% sensitivity and 98.3% specificity, while our three-class model achieved 98.3% accuracy, 99.3% sensitivity and 98.1% specificity. Moreover, via adopting a testing protocol proposed in literature, our models proved to be more robust and reliable in COVID-19 detection than a baseline ResNet8, making them good candidates for detecting COVID-19 from posteroanterior chest X-ray images.
深度学习方法在医学影像问题中已经取得了前所未有的成功。在从医学图像中检测 COVID-19 方面,也取得了类似的成功,因此深度学习方法被认为是与放射科医生和/或医生合作检测这种疾病的良好候选方法。在本文中,我们提出了一种新的方法,通过利用条件生成对抗网络来生成合成图像来增强可用的有限数量的数据,从而检测 COVID-19。此外,我们还提出了两种遵循轻量级架构的深度学习模型,与可用数据的总量相匹配。我们的实验重点是 COVID-19 与正常病例的二进制分类以及包括细菌性肺炎的第三类的多分类。与文献中的其他研究相比,我们的模型也与 ResNet8 模型相比,表现出了有竞争力的性能。我们表现最好的二进制模型达到了 98.7%的准确率、100%的敏感性和 98.3%的特异性,而我们的三分类模型达到了 98.3%的准确率、99.3%的敏感性和 98.1%的特异性。此外,通过采用文献中提出的测试方案,我们的模型在 COVID-19 检测方面比基线 ResNet8 更稳健和可靠,使它们成为从前后位胸部 X 光图像中检测 COVID-19 的良好候选方法。