Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
J Clin Hypertens (Greenwich). 2021 Mar;23(3):496-503. doi: 10.1111/jch.14163. Epub 2020 Dec 30.
Although short and long sleep duration are both risk factors of cardiovascular disease (CVD), the recent meta-analyses have been shown that long sleep duration was closely associated with CVD mortality. While the specific mechanism underlying the association between long sleep duration and CVD remains unclear, long sleep duration was shown to be associated with arterial stiffness and blood pressure variability (BPV) in many Asian populations. This review article will focus on the pathophysiology of long sleep duration, arterial stiffness, BPV and their effects on CVD. To set the stage for this review, we first summarize the current insights for the relationship between long sleep duration and CVD in relation to arterial stiffness and BPV.
尽管短时间和长时间睡眠都与心血管疾病（CVD）的风险有关，但最近的荟萃分析表明，长时间睡眠与 CVD 死亡率密切相关。虽然长时间睡眠与 CVD 之间的关联的具体机制尚不清楚，但许多亚洲人群的研究表明，长时间睡眠与动脉僵硬和血压变异性（BPV）有关。这篇综述文章将重点介绍长时间睡眠、动脉僵硬、BPV 及其对 CVD 的影响的病理生理学。为了进行综述，我们首先总结了目前关于长时间睡眠与 CVD 之间的关系，以及与动脉僵硬和 BPV 的关系的研究进展。
