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以及，来源：抗脂氧合酶和抗氧化活性的比较以及地上部分和根部提取物的化学成分。

and , Sources of : Comparison of Anti-Lipoxygenase and Antioxidant Activity as well as the Chemical Composition of Extracts from Aerial Parts and from Roots.

作者信息

Skowrońska Weronika, Granica Sebastian, Dziedzic Magdalena, Kurkowiak Justyna, Ziaja Maria, Bazylko Agnieszka

机构信息

Department of Pharmacognosy and Molecular Basis of Phytotherapy, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.

Student's Scientific Association at the Department of Pharmacognosy and Molecular Basis of Phytotherapy, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.

出版信息

Plants (Basel). 2021 Jan 2;10(1):78. doi: 10.3390/plants10010078.

DOI:10.3390/plants10010078
PMID:33401685
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7824023/
Abstract

is a weed used in traditional medicine in the treatment of skin inflammation and digestive tract diseases. is used in folk medicine interchangeably with and, according to European Medicines Agency (EMA) monography, provides an equal source of (), despite the small amount of research confirming its activity and chemical composition. The aim of the study was the comparison of the anti-lipoxygenase and the antioxidant activity, scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH), superoxide anion (O), and hydrogen peroxide (HO), of 70 % () ethanolic extracts from the aerial parts and the roots of and . In the tested extracts, the total polyphenols content and the chemical composition, analyzed with the HPLC-DAD-MS method, were also compared. The extracts were characterized by strong antioxidant properties, but their ability to inhibit lipoxygenase activity was rather weak. A correlation between the content of polyphenolic compounds and antioxidant activity was observed. The extracts from plant materials scavenged reactive oxygen species more strongly than the extracts from plant materials. Moreover, the extracts from plant materials were characterized by the statistically significantly higher content of polyphenolic compounds.

摘要

是一种用于传统医学治疗皮肤炎症和消化道疾病的杂草。根据欧洲药品管理局（EMA）的专题论文，它在民间医学中与 和 可互换使用，尽管仅有少量研究证实其活性和化学成分，但它提供了等量的 （）。本研究的目的是比较 和 地上部分及根部70%（）乙醇提取物的抗脂氧合酶和抗氧化活性、对2,2-二苯基-1-苦基肼（DPPH）、超氧阴离子（O）和过氧化氢（HO）的清除能力。同时，采用HPLC-DAD-MS方法对受试提取物中的总多酚含量和化学成分进行了比较。提取物具有较强的抗氧化性能，但其抑制脂氧合酶活性的能力较弱。观察到多酚类化合物含量与抗氧化活性之间存在相关性。 植物材料的提取物比 植物材料的提取物更能强烈地清除活性氧。此外， 植物材料的提取物具有统计学上显著更高的多酚类化合物含量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8c/7824023/6cd5ec6c1e53/plants-10-00078-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8c/7824023/8a85c7726e0b/plants-10-00078-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8c/7824023/caa7fc980936/plants-10-00078-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8c/7824023/74bbc979eb49/plants-10-00078-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8c/7824023/3d9547bc3bb9/plants-10-00078-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8c/7824023/6cd5ec6c1e53/plants-10-00078-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8c/7824023/8a85c7726e0b/plants-10-00078-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8c/7824023/caa7fc980936/plants-10-00078-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8c/7824023/74bbc979eb49/plants-10-00078-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8c/7824023/3d9547bc3bb9/plants-10-00078-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8c/7824023/6cd5ec6c1e53/plants-10-00078-g005.jpg

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