Carrillo-Ng Hugo, Becerra-Goicochea Lorena, Tarazona-Castro Yordi, Pinillos-Vilca Luis, Del Valle Luis J, Aguilar-Luis Miguel Angel, Tinco-Valdez Carmen, Silva-Caso Wilmer, Martins-Luna Johanna, Peña-Tuesta Isaac, Aquino-Ortega Ronald, Del Valle-Mendoza Juana
School of Medicine, Research and Innovation Center of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos Cuadra 2, Chorrillos, Lima, Peru.
Laboratorio de Biologia Molecular, Instituto de Investigación Nutricional, Lima, Peru.
BMC Res Notes. 2021 Jan 6;14(1):4. doi: 10.1186/s13104-020-05422-6.
To characterize the cervicovaginal microbiota of HPV-positive and HPV-negative asymptomatic Peruvian women, by identifying the presence of 13 representative bacteria genus.
A total of 100 HPV-positive and 100 HPV-negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68 vs 32%), Actinobacteria (46 vs 33%), Fusobacterium (11 vs 6%) and Bacteroides (20 vs 13%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50 vs 33.33%), Bifidobacterium (50 vs 20.83%) and Enterococcus (50 vs 29.17%).
通过鉴定13种代表性细菌属的存在情况,对秘鲁无症状HPV阳性和HPV阴性女性的宫颈阴道微生物群进行特征分析。
总共100名HPV阳性和100名HPV阴性女性按年龄匹配,以比较微生物群。与HPV阴性患者相比,HPV阳性患者中以下细菌的检出频率更高:真杆菌(68%对32%)、放线菌(46%对33%)、梭杆菌(11%对6%)和拟杆菌(20%对13%)。对高危和低危基因型进行了比较,发现放线菌(50%对33.33%)、双歧杆菌(50%对20.83%)和肠球菌(50%对29.17%)的检测存在差异。