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重组小鼠β干扰素的抗菌活性

Antibacterial activity of recombinant murine beta interferon.

作者信息

Fujiki T, Tanaka A

机构信息

Department of Biochemistry, Shimane Medical University, Izumo, Japan.

出版信息

Infect Immun. 1988 Mar;56(3):548-51. doi: 10.1128/iai.56.3.548-551.1988.

DOI:10.1128/iai.56.3.548-551.1988
PMID:3343048
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC259324/
Abstract

Recombinant murine beta interferon was protective and therapeutic for mice against Listeria monocytogenes infection in vivo. The recombinant murine beta interferon caused enhanced H2O2 release by macrophages in vivo, but not in vitro.

摘要

重组鼠β干扰素在体内对小鼠抵抗单核细胞增生李斯特菌感染具有保护和治疗作用。重组鼠β干扰素在体内可使巨噬细胞释放H2O2增加，但在体外则不然。

相似文献

1
Antibacterial activity of recombinant murine beta interferon.重组小鼠β干扰素的抗菌活性
Infect Immun. 1988 Mar;56(3):548-51. doi: 10.1128/iai.56.3.548-551.1988.
2
Protective effect of N-acetyl chitohexaose on Listeria monocytogenes infection in mice.N-乙酰壳六糖对小鼠单核细胞增生李斯特菌感染的保护作用。
Microbiol Immunol. 1989;33(4):357-67. doi: 10.1111/j.1348-0421.1989.tb01983.x.
3
Inability of recombinant interferon-gamma to activate the antibacterial activity of mouse peritoneal macrophages against Listeria monocytogenes and Salmonella typhimurium.重组干扰素-γ无法激活小鼠腹腔巨噬细胞对单核细胞增生李斯特菌和鼠伤寒沙门氏菌的抗菌活性。
J Immunol. 1987 Sep 1;139(5):1673-8.
4
Recombinant interleukin-12 enhances resistance of mice to Listeria monocytogenes infection.重组白细胞介素-12增强小鼠对单核细胞增生李斯特菌感染的抵抗力。
Microb Pathog. 1994 Sep;17(3):175-86. doi: 10.1006/mpat.1994.1064.
5
Influence of acetylsalicylic acid on a Listeria monocytogenes infection.乙酰水杨酸对单核细胞增生李斯特菌感染的影响。
Agents Actions. 1993 Sep;40(1-2):119-23. doi: 10.1007/BF01976760.
6
Neonatal Listeria monocytogenes infection is refractory to interferon.
Pediatr Res. 1991 Apr;29(4 Pt 1):400-2. doi: 10.1203/00006450-199104000-00014.
7
Murine peritoneal macrophages activated by the mycobacterial 65-kilodalton heat shock protein express enhanced microbicidal activity in vitro.由分枝杆菌65千道尔顿热休克蛋白激活的小鼠腹腔巨噬细胞在体外表现出增强的杀菌活性。
Infect Immun. 1993 Mar;61(3):868-75. doi: 10.1128/iai.61.3.868-875.1993.
8
Use of recombinant interleukin-2 to enhance adoptive transfer of resistance to Listeria monocytogenes infection.使用重组白细胞介素-2增强对单核细胞增生李斯特菌感染的抗性的过继转移。
Infect Immun. 1992 Apr;60(4):1406-14. doi: 10.1128/iai.60.4.1406-1414.1992.
9
Endogenous tumor necrosis factor (cachectin) is essential to host resistance against Listeria monocytogenes infection.内源性肿瘤坏死因子（恶病质素）对于宿主抵抗单核细胞增多性李斯特菌感染至关重要。
Infect Immun. 1988 Oct;56(10):2563-9. doi: 10.1128/iai.56.10.2563-2569.1988.
10
Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis.干扰素共有序列结合蛋白的关键作用，但干扰素调节因子1和一氧化氮合成在抵抗小鼠李斯特菌病方面均无此作用。
J Exp Med. 1997 Mar 3;185(5):921-31. doi: 10.1084/jem.185.5.921.

引用本文的文献

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For Better or Worse: Type I Interferon Responses in Bacterial Infection.无论好坏：细菌感染中的I型干扰素反应
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2
Cell-Based Screen Identifies Human Interferon-Stimulated Regulators of Listeria monocytogenes Infection.基于细胞的筛选鉴定出人类单核细胞增生李斯特菌感染的干扰素刺激调节因子。
PLoS Pathog. 2016 Dec 21;12(12):e1006102. doi: 10.1371/journal.ppat.1006102. eCollection 2016 Dec.
3
Involvement of beta interferon in enhancing inducible nitric oxide synthase production and antimicrobial activity of Burkholderia pseudomallei-infected macrophages.β干扰素在增强感染类鼻疽伯克霍尔德菌的巨噬细胞中诱导型一氧化氮合酶的产生及抗菌活性方面的作用。
Infect Immun. 2003 Jun;71(6):3053-7. doi: 10.1128/IAI.71.6.3053-3057.2003.
4
Bacterial induction of beta interferon in mice is a function of the lipopolysaccharide component.细菌在小鼠体内诱导β干扰素是脂多糖成分的一种功能。
Infect Immun. 2000 Mar;68(3):1600-7. doi: 10.1128/IAI.68.3.1600-1607.2000.
5
Pretreatment with recombinant murine tumor necrosis factor alpha/cachectin and murine interleukin 1 alpha protects mice from lethal bacterial infection.用重组鼠肿瘤坏死因子α/恶病质素和鼠白细胞介素1α进行预处理可保护小鼠免受致命细菌感染。
J Exp Med. 1989 Jun 1;169(6):2021-7. doi: 10.1084/jem.169.6.2021.
6
Enhanced resistance against Escherichia coli infection by subcutaneous administration of the hot-water extract of Chlorella vulgaris in cyclophosphamide-treated mice.在环磷酰胺处理的小鼠中，通过皮下注射普通小球藻热水提取物增强对大肠杆菌感染的抵抗力。
Cancer Immunol Immunother. 1990;32(1):1-7. doi: 10.1007/BF01741717.
7
Recombinant murine beta interferon enhances resistance of mice to systemic Mycobacterium avium infection.重组小鼠β干扰素增强小鼠对全身性鸟分枝杆菌感染的抵抗力。
Infect Immun. 1991 May;59(5):1857-9. doi: 10.1128/iai.59.5.1857-1859.1991.
8
Role of beta interferon in resistance to Toxoplasma gondii infection.β干扰素在抗弓形虫感染中的作用。
Infect Immun. 1991 Sep;59(9):3287-90. doi: 10.1128/iai.59.9.3287-3290.1991.
9
Use of immune modulators in nonspecific therapy of bacterial infections.免疫调节剂在细菌感染非特异性治疗中的应用。
Antimicrob Agents Chemother. 1992 Jan;36(1):1-5. doi: 10.1128/AAC.36.1.1.
10
Recombinant interleukin-6 protects mice against experimental bacterial infection.重组白细胞介素-6可保护小鼠免受实验性细菌感染。
Infect Immun. 1992 Oct;60(10):4402-6. doi: 10.1128/iai.60.10.4402-4406.1992.

本文引用的文献

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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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Cellular resistance to infection.细胞抗感染能力。
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Structure and expression of a cloned cDNA for mouse interferon-beta.小鼠β干扰素克隆cDNA的结构与表达
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Protection of mice against the intracellular bacterium Listeria monocytogenes by recombinant immune interferon.重组免疫干扰素对小鼠抗细胞内细菌单核细胞增生李斯特菌的保护作用。
Eur J Immunol. 1984 Oct;14(10):964-7. doi: 10.1002/eji.1830141019.
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Mouse fibroblast interferon modifies Salmonella typhimurium infection in infant mice.小鼠成纤维细胞干扰素可改变幼鼠体内鼠伤寒沙门氏菌的感染情况。
Infect Immun. 1984 Jul;45(1):62-6. doi: 10.1128/iai.45.1.62-66.1984.
6
Interferon suppresses pinocytosis but stimulates phagocytosis in mouse peritoneal macrophages: related changes in cytoskeletal organization.干扰素抑制小鼠腹腔巨噬细胞的胞饮作用，但刺激其吞噬作用：细胞骨架组织的相关变化。
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Interferon decreases production of hydrogen peroxide by macrophages: correlation with reduction of suppressive capacity and of anti-microbial activity.干扰素可降低巨噬细胞过氧化氢的产生：与抑制能力和抗菌活性降低相关。
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8
The significance of alpha/beta interferons and gamma interferon produced in mice infected with Listeria monocytogenes.感染单核细胞增生李斯特菌的小鼠体内产生的α/β干扰素和γ干扰素的意义。
Cell Immunol. 1984 Oct 1;88(1):29-40. doi: 10.1016/0008-8749(84)90049-2.
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Effect of a homologous beta-interferon preparation on degradation of Escherichia coli and on lysosomal enzyme activities in mouse peritoneal macrophages.同源β-干扰素制剂对小鼠腹腔巨噬细胞中大肠杆菌降解及溶酶体酶活性的影响。
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