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基于纳米纤维素的创伤敷料在儿童二度烧伤保守性伤口管理中的应用。

Nanocellulose-based wound dressing for conservative wound management in children with second-degree burns.

机构信息

Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria.

出版信息

Int Wound J. 2021 Aug;18(4):478-486. doi: 10.1111/iwj.13548. Epub 2021 Jan 19.

Abstract

The initial care of burn wounds and choice of dressing are pivotal to optimally support the healing process. To ensure fast re-epithelialisation within 10-14 days and prevent complications, an optimal healing environment is essential. An innovative dressing based on nanocellulose was used for the treatment of burns in children. Children (0-16 years) with clean, partial-thickness burn wounds, 1 to 10% of the total body surface area were included. Complete re-epithelialisation was achieved within 7-17 days, with 13 patients showing re-epithelialised >95% by day 10. Satisfying results concerning time to re-epithelialisation and material handling were obtained. The possibility to leave the dressing on the wounds for 7 days showed a positive effect in the treatment of children, for whom every hospital visit may cause massive stress reactions. The nanocellulose-based dressing is a promising tool in conservative treatment of burns. Reducing the frequency of dressing changes supports a fast and undisturbed recovery; moreover, the dressing provides an optimal moist healing environment. The time to re-epithelialisation is comparable to frequently used materials, and cost reduction effect can be achieved without loss of quality. Possible pain and distress levels are kept to a minimum; therefore, flexibility and compliance of the patients and their parents are enhanced.

摘要

烧伤创面的初期处理和敷料选择对优化创面愈合过程至关重要。为了确保在 10-14 天内快速上皮化并预防并发症,必须创造一个理想的愈合环境。一种基于纳米纤维素的新型敷料已被用于儿童烧伤的治疗。纳入的儿童(0-16 岁)的烧伤创面为清洁的、部分厚度烧伤,面积占体表面积的 1%至 10%。13 名患者在第 10 天就达到了>95%的完全上皮化,7-17 天内实现了完全上皮化。在实现上皮化的时间和材料处理方面取得了满意的效果。将敷料保留在创面 7 天的可能性对儿童治疗产生了积极影响,因为每次去医院就诊都可能引发巨大的应激反应。基于纳米纤维素的敷料是保守治疗烧伤的一种有前途的工具。减少更换敷料的频率有助于快速、不受干扰的恢复,而且敷料还提供了一个理想的湿润愈合环境。实现上皮化的时间与常用材料相当,而且在不降低质量的情况下可以实现成本降低效果。可能的疼痛和不适程度保持在最低水平,因此增强了患者及其父母的灵活性和顺应性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bed/8273580/df9662b1b0b3/IWJ-18-478-g006.jpg

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