Marin Clara, Lorenzo-Rebenaque Laura, Laso Omar, Villora-Gonzalez José, Vega Santiago
Facultad de Veterinaria, Instituto de Ciencias Biomédicas, Universidad Cardenal Herrera-CEU, CEU Universities, Alfara del Patriarca, Spain.
Selvätica Veterinary Clinic, Valencia, Spain.
Front Vet Sci. 2021 Jan 6;7:613718. doi: 10.3389/fvets.2020.613718. eCollection 2020.
spp. is widely considered one of the most important zoonotic pathogens worldwide. The close contact between reptiles and their owners provides favourable conditions for the transmission of zoonotic pathogen infections, and ~6% of human salmonellosis cases are acquired after direct or indirect contact with reptiles. Moreover, antimicrobial resistance is one of the most important health threats of the twenty-first century and has been reported in strains isolated from pet reptiles, which could entail therapeutic consequences for their owners and breeders. The aim of this study was to assess carriage by pet reptiles in pet shops and households, and their role in the transmission of antimicrobial resistance, to inform the owners about the possible risks factors. During the period between January 2019 and December 2019, 54 reptiles from pet shops and 69 reptiles from households were sampled in the Valencian Region (Eastern Spain). Three different sample types were collected from each reptile: oral cavity, skin, and cloacal swabs. identification was based on ISO 6579-1:2017 (Annex D), serotyped in accordance with Kauffman-White-Le-Minor technique, and antibiotic susceptibility was assessed according to Decision 2013/652. The results of this study showed that 48% of the pet reptiles examined from households and pet shops carry spp. All the strains isolated presented resistance to at least one antibiotic, and 72% were multidrug-resistant strains, the most frequently observed resistance patterns being gentamicin-colistin and gentamicin-colistin-ampicillin. The present study demonstrates that pet reptiles could be a source of human multidrug-resistant infection. In this context, the most optimal prevention of multidrug-resistant infections necessarily involves strict control of the sanitary status of reptile pet shops and hygienic handling by the individual owners at home.
沙门氏菌属被广泛认为是全球最重要的人畜共患病原体之一。爬行动物与其主人之间的密切接触为动物源性病原体感染的传播提供了有利条件，约6%的人类沙门氏菌病病例是在直接或间接接触爬行动物后感染的。此外，抗菌药物耐药性是21世纪最重要的健康威胁之一，在从宠物爬行动物分离出的菌株中已有报道，这可能给其主人和饲养者带来治疗方面的后果。本研究的目的是评估宠物店和家庭中宠物爬行动物携带沙门氏菌的情况及其在抗菌药物耐药性传播中的作用，以便让主人了解可能的风险因素。在2019年1月至2019年12月期间，在巴伦西亚地区（西班牙东部）对来自宠物店的54只爬行动物和来自家庭的69只爬行动物进行了采样。从每只爬行动物采集三种不同的样本类型：口腔、皮肤和泄殖腔拭子。沙门氏菌的鉴定依据ISO 6579-1:2017（附录D），按照考夫曼-怀特-勒-米诺技术进行血清分型，并根据2013/652号决定评估抗生素敏感性。本研究结果表明，从家庭和宠物店检查的宠物爬行动物中有48%携带沙门氏菌属。所有分离出的菌株对至少一种抗生素耐药，72%为多重耐药菌株，最常见的耐药模式是庆大霉素-黏菌素和庆大霉素-黏菌素-氨苄西林。本研究表明，宠物爬行动物可能是人类多重耐药沙门氏菌感染的一个来源。在此背景下，预防多重耐药沙门氏菌感染的最佳方法必然包括严格控制爬行动物宠物店的卫生状况以及主人在家中的卫生处理。
