School of Electrical Engineering, VIT University, Tamilnadu, India.
School of Electrical Engineering, VIT University, Tamilnadu, India.
J Infect Public Health. 2021 Feb;14(2):249-259. doi: 10.1016/j.jiph.2020.12.020. Epub 2020 Dec 29.
A number of unexplained cases of pneumonia have been recorded since November 2019 in China. It is officially named the new corona virus (2019-nCov) by the World Health Organization on 12 January 2020. WHO officially named it COVID-19 on 11 February. COVID-19 is a highly transmitted and pathogenic viral infection that has been developed and spread across the world in Wuhan, China, caused by extreme acute respiratory syndrome corona-virus 2 (SARS-CoV-2). Genomic analysis showed that bats may also be a primary reservoir of SARS-CoV-2 phylogenetically associated with severe acute respiratory syndrome-like viruses (SARS). However, the rapid human to human transition has been generally reported. Intermediate source of origin and human transition is unknown. Clinically approved COVID-19 antiviral medication or vaccine is not available. In clinical trials, however, few broad-based COVID-19 antiviral medicinal drugs were tested, resulting in clinical recovery. This analysis summarizes the pathogenicity of COVID-19 and aims to raise awareness of COVID-19 among the population and to continually boost the detection, monitoring, diagnosis and care level. Over 50 COVID-19 scientific publications were included in this systematic analysis. We found that fever (87.0%), cough (65.9%) and malaise/tiredness (35%) were the most common symptoms of COvida-19. However, COVID-19 clinical signs and symptoms were not necessarily obvious. The transmission of COVID-19 in comparison to SARS was more specific. The rate of death of COVID-19 was 2,7% and the pathological characteristics of COVID-19 are very similar to ARDS. There are also discussions on the latest epidemiological changes, clinical manifestations, auxiliary examination and COVID-19 pathological characteristics.
自 2019 年 11 月以来，中国已记录到多起不明原因肺炎病例。2020 年 1 月 12 日，世界卫生组织正式将其命名为新型冠状病毒（2019-nCov）。2 月 11 日，世界卫生组织正式将其命名为 COVID-19。COVID-19 是一种高度传染性和致病性的病毒感染，由极端急性呼吸系统综合征冠状病毒 2（SARS-CoV-2）在中国武汉发展和传播。基因组分析表明，蝙蝠也可能是 SARS-CoV-2 的主要宿主，其在系统发育上与严重急性呼吸系统综合征样病毒（SARS）有关。然而，据报道，这种病毒已迅速在全世界传播。中间来源和人际传播尚不清楚。目前还没有经过临床批准的 COVID-19 抗病毒药物或疫苗。然而，在临床试验中，仅测试了少数几种广泛的 COVID-19 抗病毒药物，从而导致临床康复。本分析总结了 COVID-19 的发病机制，旨在提高公众对 COVID-19 的认识，并不断提高检测、监测、诊断和护理水平。本系统分析共纳入了 50 多篇关于 COVID-19 的科学出版物。我们发现，发热（87.0%）、咳嗽（65.9%）和不适/乏力（35%）是 COVID-19 的最常见症状。然而，COVID-19 的临床症状并不一定明显。与 SARS 相比，COVID-19 的传播更为特定。COVID-19 的死亡率为 2.7%，其病理特征与 ARDS 非常相似。还讨论了最新的流行病学变化、临床表现、辅助检查和 COVID-19 的病理特征。
