Faculty of Pharmaceutical Sciences, UCSI University, No. 1, Jalan Menara Gading, Taman Connaught, Cheras 56000, Kuala Lumpur, Malaysia.
Curr Pharm Des. 2021;27(21):2482-2504. doi: 10.2174/1381612827666210127121347.
This review article mainly focuses on the revolution of the synthesis of gold nanoplatform from the previous era to the present era. Initially, the gold nanoplatform was widely used by the electrical and electronic industries for their products due to its remarkable properties, such as large surface volume, redox activity, fluorescence quenching, and optical-electronic properties. In this era, due to the invention of localised surface plasmonic resonance, optoacoustic, photothermal and theragnostic characteristics of the gold nanoplatforms and their application in biosensors and various diagnostic methods, the pharmaceutical and biotechnological companies have started showing their interest in manufacturing gold nanoplatforms for their new product development. This colloidal dispersion is synthesized in various forms, such as a gold nanoparticle, gold nanoplatform, plasmonic gold nanoparticle, amphiphilic gold nanoparticle, and gold nanocrystal. This review article describes various methods for preparation of gold nanoplatforms with different size, shape, and physiobiological properties and their applications in different fields.
这篇综述文章主要聚焦于金纳米平台从过去到现在的合成革命。最初，由于其显著的性质，如大的表面积体积、氧化还原活性、荧光猝灭和光电性质，金纳米平台被电气和电子行业广泛应用于他们的产品中。在这个时代，由于局部表面等离激元共振、光声、光热和金纳米平台的治疗诊断特性及其在生物传感器和各种诊断方法中的应用，制药和生物技术公司已经开始表现出对制造金纳米平台以开发其新产品的兴趣。这种胶体分散体以各种形式合成，如金纳米颗粒、金纳米平台、等离子体金纳米颗粒、两亲金纳米颗粒和金纳米晶体。本文综述了制备具有不同尺寸、形状和生理生物特性的金纳米平台的各种方法及其在不同领域的应用。
