Suppr超能文献

健康老年人和年轻人的计算机化认知训练:总体效果及对认知的选择性影响的年龄比较

Computerized Cognitive Training by Healthy Older and Younger Adults: Age Comparisons of Overall Efficacy and Selective Effects on Cognition.

作者信息

Ng Nicole F, Osman Allen M, Kerlan Kelsey R, Doraiswamy P Murali, Schafer Robert J

机构信息

Department of Research and Development, Lumos Labs, San Francisco, CA, United States.

Duke University School of Medicine, Neurocognitive Disorders Program, Department of Psychiatry and Behavioral Sciences, Duke Institute for Brain Sciences, Durham, NC, United States.

出版信息

Front Neurol. 2021 Jan 8;11:564317. doi: 10.3389/fneur.2020.564317. eCollection 2020.

Abstract

Among the non-pharmacological methods under development for maintaining cognitive function across the lifespan is computerized cognitive training (CCT). There has been considerable interest in using CCT to slow or remediate age-related cognitive decline, both normal and pathological. Toward these ends, it would be useful to know how the effects of CCT on cognitive function vary over the course of normal cognitive aging. Are there changes in either 1) the overall efficacy of CCT or 2) which cognitive faculties are affected? To address these two questions, we reanalyzed results from a large online study by Hardy et al. (1) of 4,715 adults between 18 and 80 that examined effects of CCT on both a neuropsychological test battery and self-reported ratings of cognition and affect in daily living. Combined across all participants, Hardy et al. found greater improvement on both types of assessment following 10 weeks of CCT with the commercial program Lumosity, as compared to practice with a control activity involving computerized crossword puzzles. The present study compared the size of these effects on the older (50-80) and younger (18-49) participants. To address the question of overall efficacy, we examined CCT effects (treatment minus control) on overall performance of the test battery and mean rating. No significant difference on either measure was found between the two age cohorts. To address the question of whether the same magnitude of overall effects on both age cohorts was due to equivalent effects on the same set of underlying cognitive functions, we examined the patterns of CCT effects across individual subtests and rated items. These patterns did not differ significantly between the two age cohorts. Our findings suggest that benefits from CCT can occur to a similar degree and in a similar way across an extended part of the adult lifespan. Moreover, the overall effects of CCT delivered over the internet were of the same small to medium size as those typically found in the lab or clinic. Besides improving access and reducing the cost of CCT for older adults, delivery over the internet makes long-term training more practicable, which could potentially yield larger benefits.

摘要

在为维持整个生命周期的认知功能而正在研发的非药物方法中,计算机化认知训练(CCT)是其中之一。人们对使用CCT来减缓或补救与年龄相关的认知衰退(包括正常和病理性衰退)有着浓厚兴趣。为了实现这些目标,了解CCT对认知功能的影响在正常认知衰老过程中如何变化将是很有用的。1)CCT的总体功效或2)哪些认知能力受到影响这两方面会有变化吗?为了解决这两个问题,我们重新分析了哈迪等人(1)对4715名18至80岁成年人进行的一项大型在线研究的结果,该研究考察了CCT对一套神经心理测试组合以及日常生活中认知和情感的自我报告评分的影响。综合所有参与者的数据,哈迪等人发现,与进行涉及计算机化纵横字谜的对照活动相比,使用商业程序Lumosity进行10周的CCT后,在这两种评估类型上都有更大的改善。本研究比较了这些影响在年龄较大(50 - 80岁)和年龄较小(18 - 49岁)参与者身上的大小。为了解决总体功效问题,我们考察了CCT对测试组合的总体表现和平均评分的影响(治疗减去对照)。在这两项指标上,两个年龄组之间均未发现显著差异。为了解决两个年龄组总体影响程度相同是否是由于对同一组潜在认知功能的等效影响这一问题,我们考察了CCT在各个子测试和评分项目上的影响模式。这两个年龄组之间的这些模式没有显著差异。我们的研究结果表明,在成年生命周期的较长阶段,CCT带来的益处可以以相似的程度和方式出现。此外,通过互联网提供的CCT的总体影响与通常在实验室或诊所中发现的影响大小相同,为中到小。除了改善老年人获取CCT的机会并降低成本外,通过互联网提供CCT使长期训练更可行,这可能会带来更大的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a21/7832391/f466aa194b0e/fneur-11-564317-g0001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验