Center for Grain and Animal Health Research, Agricultural Research Service, United States Department of Agriculture, Manhattan, KS 66502, USA.
Arboviral Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA.
Viruses. 2021 Feb 2;13(2):226. doi: 10.3390/v13020226.
Oropouche virus (OROV), a vector-borne circulating in South and Central America, causes a febrile illness with high rates of morbidity but with no documented fatalities. Oropouche virus is transmitted by numerous vectors, including multiple genera of mosquitoes and biting midges in South America. This study investigated the vector competence of three North American vectors, , and , for OROV. Cohorts of each species were fed an infectious blood meal containing 6.5 log PFU/mL OROV and incubated for 10 or 14 days. demonstrated infection (3.13%) but not dissemination or transmission potential at 10 days post infection (DPI). At 10 and 14 DPI, demonstrated 9.71% and 19.3% infection, 2.91% and 1.23% dissemination, and 0.97% and 0.82% transmission potential, respectively. demonstrated 86.63% infection, 83.14% dissemination, and 19.77% transmission potential at 14 DPI. Based on these data, is unlikely to be a competent vector for OROV. demonstrated infection, dissemination, and transmission potential, although at relatively low rates. demonstrated high infection and dissemination but may have a salivary gland barrier to the virus. These data have implications for the spread of OROV in the event of a North American introduction.
奥罗普切病毒（OROV）是一种在南美洲和中美洲循环传播的虫媒病毒，可引起高热病，发病率高，但无死亡记录。OROV 通过多种媒介传播，包括南美的多个蚊子属和吸血蠓属。本研究调查了三种北美的媒介，即 、 和 对 OROV 的媒介效能。每个物种的队列都被喂食了含有 6.5 log PFU/mL OROV 的感染性血液餐，并在 10 或 14 天内孵育。在 10 天和 14 天的 DPI 时， 显示出 3.13%的感染率，但没有传播或传播潜力。在 10 和 14 DPI 时， 分别显示出 9.71%和 19.3%的感染率、2.91%和 1.23%的传播率以及 0.97%和 0.82%的传播潜力。在 14 DPI 时， 显示出 86.63%的感染率、83.14%的传播率和 19.77%的传播潜力。基于这些数据， 不太可能是 OROV 的有效媒介。 显示出感染、传播和传播潜力，尽管相对较低。 显示出高感染和传播率，但可能存在病毒的唾液腺屏障。这些数据对 OROV 在北美引入的情况下的传播有影响。
