Department of Cardiology, Umraniye Training and Research Hospital, University of Health Sciences, Elmalıkent, Adem Yavuz Cd., Ümraniye, 34764, Istanbul, Turkey.
Department of Cardiology, Gaziantep Abdülkadir Yüksel State Hospital, Gaziantep, Turkey.
Int J Cardiovasc Imaging. 2021 Jun;37(6):1883-1890. doi: 10.1007/s10554-021-02171-w. Epub 2021 Feb 8.
It has been reported that myocardial damage and heart failure are more common in COVID-19 patients with severe symptoms. The aim of our study was to measure the right ventricular functions of COVID-19 patients 30 days after their discharge, and compare them to the right ventricular functions of healthy volunteers. Fifty one patients with COVID-19 and 32 healthy volunteers who underwent echocardiographic examinations were enrolled in our study. 29 patients were treated for severe and 22 patients were treated for moderate COVID-19 pneumonia. The study was conducted prospectively, in a single center, between 15 May 2020 and 15 July 2020. We analyzed the right ventricular functions of the patients using conventional techniques and two-dimensional speckle-tracking. Right ventricular end-diastolic and end-systolic area were statistically higher than control group. The right ventricular fractional area change (RVFAC) was significantly lesser in the patient group compared to the control group. Tricuspid annular plane systolic motion (TAPSE) was within normal limits in both groups, it was lower in the patient group compared to the control group. Pulmonary artery pressure was found to be significantly higher in the patient group. Right ventricular global longitudinal strain (RV-GLS) was lesser than the control group (- 15.7 [(- 12.6)-(- 18.7)] vs. - 18.1 [(- 14.8)-(- 21)]; p 0.011). Right ventricular free wall strain (RV-FWS) was lesser in the patient group compared to the control group (- 16 [(- 12.7)-(- 19)] vs - 21.6 [(- 17)-(- 25.3)]; p < 0.001). We found subclinical right ventricular dysfunction in the echocardiographies of COVID-19 patients although there were no risk factors.
据报道，重症 COVID-19 患者的心肌损伤和心力衰竭更为常见。本研究旨在测量 COVID-19 患者出院后 30 天的右心室功能，并将其与健康志愿者的右心室功能进行比较。我们纳入了 51 例 COVID-19 患者和 32 例健康志愿者进行超声心动图检查。29 例患者接受重症 COVID-19 肺炎治疗，22 例患者接受中度 COVID-19 肺炎治疗。这项研究是在 2020 年 5 月 15 日至 7 月 15 日期间在一家单中心前瞻性进行的。我们使用常规技术和二维斑点追踪技术分析患者的右心室功能。右心室舒张末期和收缩末期面积明显高于对照组。与对照组相比，患者组的右心室射血分数（RVFAC）明显降低。两组三尖瓣环平面收缩期运动（TAPSE）均在正常范围内，但患者组低于对照组。患者组肺动脉压明显升高。右心室整体纵向应变（RV-GLS）低于对照组（-15.7[-12.6 到-18.7] 比 -18.1[-14.8 到-21]；p=0.011）。与对照组相比，患者组右心室游离壁应变（RV-FWS）较低（-16[-12.7 到-19]比 -16[-17 到-25.3]；p<0.001）。尽管没有危险因素，但我们在 COVID-19 患者的超声心动图中发现了亚临床右心室功能障碍。
