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中药作为电离辐射诱导损伤治疗选择的疗效及机制综述

Review of the Efficacy and Mechanisms of Traditional Chinese Medicines as a Therapeutic Option for Ionizing Radiation Induced Damage.

作者信息

Zhang Xiaomeng, Chen Xiaoying, Wang Lei, He Changhao, Shi Zhongyu, Fu Qian, Xu Wenhui, Zhang Shujing, Hu Sumin

机构信息

School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.

Beijing Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.

出版信息

Front Pharmacol. 2021 Feb 15;12:617559. doi: 10.3389/fphar.2021.617559. eCollection 2021.

Abstract

Ionizing radiation damage refers to acute, delayed, or chronic tissue damage associated with ionizing radiation. Specific or effective therapeutic options for systemic injuries induced by ionizing radiation have not been developed. Studies have shown that Chinese herbal Medicine or Chinese Herbal Prescription exhibit preventive properties against radiation damage. These medicines inhibit tissue injuries and promote repair with very minimal side effects. This study reviews traditional Chinese herbal medicines and prescriptions with radiation protective effects as well as their mechanisms of action. The information obtained will guide the development of alternative radioprotectants.

摘要

电离辐射损伤是指与电离辐射相关的急性、延迟性或慢性组织损伤。目前尚未开发出针对电离辐射所致全身损伤的特效治疗方法。研究表明,中草药或中药方剂具有预防辐射损伤的特性。这些药物能抑制组织损伤并促进修复,且副作用极小。本研究综述了具有辐射防护作用的传统中草药及方剂及其作用机制。所获信息将为新型辐射防护剂的研发提供指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4fe/7917257/5dffc3cf407f/fphar-12-617559-g001.jpg

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