Rajivgandhi Govindan Nadar, Kanisha Chelliah Chenthis, Ramachandran Govindan, Manoharan Natesan, Mothana Ramzi A, Siddiqui Nasir A, Al-Rehaily Adnan J, Ullah Riaz, Almarfadi Omer M
Department of Marine Science, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu, India.
Noorul Islam Centre for Higher Education, Kumaracoil, Kanyakumari, Tamil Nadu 629180, India.
Saudi J Biol Sci. 2021 Mar;28(3):1763-1769. doi: 10.1016/j.sjbs.2020.12.018. Epub 2021 Jan 6.
In this study, the phytochemical, phenolic, flavonoid and bioactive compounds were successfully screened from crude extract of by LC-MS analysis after NIST interpretation. Bacterial growth inhibition study result was shown with 24 mm zone inhibition at 200 µg/mL concentration against . The increased phenolic content was much closed to gallic acid and the range was observed at 250 μg/mL concentration. In addition, flavonoid contents of the algae extract was indicated more significant with rutin at 200 μg/mL. In result, both the phenolic and flavonoid contents of the extract were more correlated with gallic acid and rutin. Further, the total anti-oxidant and DPPH radical scavenging activities were shown increased activity at 200 μg/mL concentrations. Furthermore, the excellent anti-bacterial alteration result was observed at 200 μg/mL concentration by minimum inhibition concentration. Therefore, the result was revealed that the marine algae has excellent phytochemical and anti-oxidant activities, and it has improved anti-bacterial activity against .
在本研究中,通过LC-MS分析并经NIST解释后,成功从[藻类名称未给出]的粗提物中筛选出植物化学物质、酚类、黄酮类和生物活性化合物。细菌生长抑制研究结果表明,在200μg/mL浓度下对[细菌名称未给出]的抑菌圈为24mm。酚类含量增加,与没食子酸非常接近,在250μg/mL浓度下观察到该范围。此外,藻类提取物的黄酮类含量在200μg/mL时以芦丁表示更为显著。结果表明,提取物的酚类和黄酮类含量与没食子酸和芦丁的相关性更强。此外,总抗氧化和DPPH自由基清除活性在200μg/mL浓度下表现出增加的活性。此外,通过最低抑菌浓度在200μg/mL浓度下观察到优异的抗菌变化结果。因此,结果表明该海藻具有优异的植物化学和抗氧化活性,并且对[细菌名称未给出]具有增强的抗菌活性。