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神经网络模型辅助傅里叶叠层术的泽尼克像差恢复和全变分约束。

Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint.

机构信息

Tsinghua Univ. Shenzhen International Graduate School, China.

Harbin Institute of Technology, China.

出版信息

J Biomed Opt. 2021 Mar;26(3). doi: 10.1117/1.JBO.26.3.036502.

Abstract

SIGNIFICANCE

Fourier ptychography (FP) is a computational imaging approach that achieves high-resolution reconstruction. Inspired by neural networks, many deep-learning-based methods are proposed to solve FP problems. However, the performance of FP still suffers from optical aberration, which needs to be considered.

AIM

We present a neural network model for FP reconstructions that can make proper estimation toward aberration and achieve artifact-free reconstruction.

APPROACH

Inspired by the iterative reconstruction of FP, we design a neural network model that mimics the forward imaging process of FP via TensorFlow. The sample and aberration are considered as learnable weights and optimized through back-propagation. Especially, we employ the Zernike terms instead of aberration to decrease the optimization freedom of pupil recovery and perform a high-accuracy estimation. Owing to the auto-differentiation capabilities of the neural network, we additionally utilize total variation regularization to improve the visual quality.

RESULTS

We validate the performance of the reported method via both simulation and experiment. Our method exhibits higher robustness against sophisticated optical aberrations and achieves better image quality by reducing artifacts.

CONCLUSIONS

The forward neural network model can jointly recover the high-resolution sample and optical aberration in iterative FP reconstruction. We hope our method that can provide a neural-network perspective to solve iterative-based coherent or incoherent imaging problems.

摘要

意义

傅里叶叠层术(FP)是一种实现高分辨率重建的计算成像方法。受神经网络启发,提出了许多基于深度学习的方法来解决 FP 问题。然而,FP 的性能仍然受到像差的影响,这需要加以考虑。

目的

我们提出了一种用于 FP 重建的神经网络模型,该模型可以对像差进行适当的估计,并实现无伪影的重建。

方法

受 FP 迭代重建的启发,我们设计了一个神经网络模型,通过 TensorFlow 模拟 FP 的正向成像过程。样本和像差被视为可学习的权重,并通过反向传播进行优化。特别是,我们采用泽尼克项代替像差,以减少瞳孔恢复的优化自由度,并进行高精度的估计。由于神经网络的自动微分功能,我们还额外利用全变差正则化来提高视觉质量。

结果

我们通过模拟和实验验证了所提出方法的性能。与复杂的光学像差相比,我们的方法表现出更高的鲁棒性,并通过减少伪影来实现更好的图像质量。

结论

正向神经网络模型可以在迭代 FP 重建中联合恢复高分辨率样本和光学像差。我们希望我们的方法能够为解决基于迭代的相干或非相干成像问题提供一个神经网络的视角。

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