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用于生物医学应用的天然生物基单体:综述

Natural bio-based monomers for biomedical applications: a review.

作者信息

Birajdar Mallinath S, Joo Haejin, Koh Won-Gun, Park Hansoo

机构信息

Department of Integrative Engineering, Chung-Ang University, Seoul, Republic of Korea.

Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, Republic of Korea.

出版信息

Biomater Res. 2021 Apr 1;25(1):8. doi: 10.1186/s40824-021-00208-8.

Abstract

In recent years, synthetic and semi-synthetic polymer materials have been widely used in various applications. Especially concerning biomedical applications, their biocompatibility, biodegradability, and non-toxicity have increased the interest of researchers to discover and develop new products for the well-being of humanity. Among the synthetic and semi-synthetic materials, the use of natural bio-based monomeric materials presents a possible novel avenue for the development of new biocompatible, biodegradable, and non-toxic products. The purpose of this article is to review the information on the role of natural bio-based monomers in biomedical applications. Increased eco-friendliness, biocompatibility, biodegradability, non-toxicity, and intrinsic biological activity are some of the attributes which make itaconic, succinic, citric, hyaluronic, and glutamic acids suitable potential materials for biomedical applications. Herein, we summarize the most recent advances in the field over the past ten years and specifically highlight new and interesting discoveries in biomedical applications. Natural origin acid-based bio-monomers for biomedical applications.

摘要

近年来,合成和半合成聚合物材料已广泛应用于各种领域。特别是在生物医学应用方面,它们的生物相容性、生物降解性和无毒特性激发了研究人员的兴趣,促使他们为人类福祉研发新产品。在合成和半合成材料中,使用天然生物基单体材料为开发新型生物相容、可生物降解和无毒产品提供了一条可能的新途径。本文旨在综述天然生物基单体在生物医学应用中的作用相关信息。生态友好性增强、生物相容性、生物降解性、无毒以及内在生物活性等特性,使衣康酸、琥珀酸、柠檬酸、透明质酸和谷氨酸成为生物医学应用中潜在的合适材料。在此,我们总结了过去十年该领域的最新进展,并特别强调了生物医学应用中的新发现和有趣成果。用于生物医学应用的天然来源酸基生物单体。

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