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Aging and monocyte immunometabolism in COVID-19.

作者信息

Pence Brandt D

机构信息

College of Health Sciences, University of Memphis, Memphis, TN 38152, USA.

Center for Nutraceutical and Dietary Supplement Research, University of Memphis, Memphis, TN 38152, USA.

出版信息

Aging (Albany NY). 2021 Mar 30;13(7):9154-9155. doi: 10.18632/aging.202918.

DOI:10.18632/aging.202918
PMID:33795524
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8064183/
Abstract
摘要

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本文引用的文献

1
Aging, Immunity, and COVID-19: How Age Influences the Host Immune Response to Coronavirus Infections?衰老、免疫与2019冠状病毒病：年龄如何影响宿主对冠状病毒感染的免疫反应？
Front Physiol. 2021 Jan 12;11:571416. doi: 10.3389/fphys.2020.571416. eCollection 2020.
2
Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators.脂滴为 SARS-CoV-2 的复制和炎症介质的产生提供燃料。
PLoS Pathog. 2020 Dec 16;16(12):e1009127. doi: 10.1371/journal.ppat.1009127. eCollection 2020 Dec.
3
Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis.高血糖水平通过 HIF-1α/糖酵解依赖轴促进 SARS-CoV-2 感染和单核细胞反应。
Cell Metab. 2020 Sep 1;32(3):437-446.e5. doi: 10.1016/j.cmet.2020.07.007. Epub 2020 Jul 17.
4
Factors associated with COVID-19-related death using OpenSAFELY.使用 OpenSAFELY 分析与 COVID-19 相关死亡的因素。
Nature. 2020 Aug;584(7821):430-436. doi: 10.1038/s41586-020-2521-4. Epub 2020 Jul 8.
5
Severe COVID-19 and aging: are monocytes the key?严重 COVID-19 与衰老：单核细胞是关键吗？
Geroscience. 2020 Aug;42(4):1051-1061. doi: 10.1007/s11357-020-00213-0. Epub 2020 Jun 15.
6
Monocytes present age-related changes in phospholipid concentration and decreased energy metabolism.单核细胞呈现出与年龄相关的磷脂浓度变化以及能量代谢降低。
Aging Cell. 2020 Apr;19(4):e13127. doi: 10.1111/acel.13127. Epub 2020 Feb 27.
7
Aging impairs mitochondrial respiratory capacity in classical monocytes.衰老会损害经典单核细胞中线粒体的呼吸能力。
Exp Gerontol. 2018 Jul 15;108:112-117. doi: 10.1016/j.exger.2018.04.008. Epub 2018 Apr 13.
8
Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function.衰老是与慢性固有免疫激活以及单核细胞表型和功能失调相关联的。
Aging Cell. 2012 Oct;11(5):867-75. doi: 10.1111/j.1474-9726.2012.00851.x. Epub 2012 Jul 20.