探索光声成像对乳腺癌的诊断价值：乳腺肿瘤区域光声信号差异的识别
Exploring the diagnostic value of photoacoustic imaging for breast cancer: the identification of regional photoacoustic signal differences of breast tumors.
作者信息
Zhang Rui, Zhao Ling-Yi, Zhao Chen-Yang, Wang Ming, Liu Si-Rui, Li Jian-Chu, Zhao Rui-Na, Wang Ruo-Jiao, Yang Fang, Zhu Lei, He Xu-Jin, Li Chang-Hui, Jiang Yu-Xin, Yang Meng
机构信息
Department of Ultrasound, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of Biomedical Engineering, College of Engineering, Peking University, Beijing, China.
出版信息
Biomed Opt Express. 2021 Feb 16;12(3):1407-1421. doi: 10.1364/BOE.417056. eCollection 2021 Mar 1.
Abstract
We examined 14 benign and 26 malignant breast nodules by a handheld dual-modal PA/US imaging system and analyzed the data using the quantitative and semi-quantitative method. The and PA scores of different regions of the benign and malignant nodules were compared, and the diagnostic performances of two diagnostic methods based on PA parameters were evaluated. For both quantitative and semi-quantitative results, significant differences in the distributions of PA signals in different regions of benign and malignant breast lesions were identified. The PA parameters showed good performance in diagnosing breast cancer, indicating the potential of PAI in clinical utilization.
摘要
我们使用手持式双模态光声/超声成像系统对14个良性和26个恶性乳腺结节进行了检查，并采用定量和半定量方法对数据进行了分析。比较了良性和恶性结节不同区域的光声和超声评分，并评估了基于光声参数的两种诊断方法的诊断性能。对于定量和半定量结果，均发现良性和恶性乳腺病变不同区域的光声信号分布存在显著差异。光声参数在乳腺癌诊断中表现良好，表明光声成像在临床应用中的潜力。
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