Department of Social Medicine and Public Health, Medical University of Warsaw, Oczki Street 3, 02-007 Warsaw, Poland.
Viruses. 2021 Mar 24;13(4):534. doi: 10.3390/v13040534.
The disinfection of surfaces in medical facilities is an important element of infection control, including the control of viral infections such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Preparations used for surface disinfection are typically characterized via their activity against test organisms (i.e., viruses, bacteria and fungi) in the laboratory. Typically, these methods use a suspension of the test organism to assess the bactericidal, fungicidal or virucidal activity of a given preparation. However, such suspension methods do not fully imitate real-life conditions. To address this issue, carrier methods have been developed, in which microorganisms are applied to the surface of a carrier (e.g., stainless steel, glass and polyvinyl chloride (PVC)) and then dried. Such methods more accurately reflect the applications in real-life clinical practice. This article summarizes the available methods for assessing the virucidal activity of chemical disinfectants for use in medical facilities based on the current European standards, including the activity against coronaviruses.
医疗机构表面的消毒是感染控制的一个重要环节，包括对严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）等病毒感染的控制。用于表面消毒的制剂通常通过其在实验室中对测试生物（即病毒、细菌和真菌）的活性来表征。通常，这些方法使用测试生物的悬浮液来评估给定制剂的杀菌、杀菌或杀病毒活性。然而，这种悬浮方法不能完全模拟现实生活中的情况。为了解决这个问题，已经开发了载体方法，其中将微生物施加到载体（例如不锈钢、玻璃和聚氯乙烯（PVC））的表面上，然后使其干燥。这种方法更准确地反映了现实生活中临床实践中的应用。本文总结了基于当前欧洲标准评估医疗设施用化学消毒剂杀病毒活性的可用方法，包括对冠状病毒的活性。
