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Reevaluation of the non-lesional dry skin in atopic dermatitis by acute barrier disruption: an abnormal permeability barrier homeostasis with defective processing to generate ceramide.通过急性屏障破坏对特应性皮炎中非皮损性干性皮肤的重新评估：一种具有生成神经酰胺加工缺陷的异常渗透屏障稳态。
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本文引用的文献

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hiPSC-Derived Epidermal Keratinocytes from Ichthyosis Patients Show Altered Expression of Cornification Markers.从鱼鳞病患者中诱导的多能干细胞衍生的表皮角质形成细胞显示出细胞角质化标志物表达的改变。
Int J Mol Sci. 2021 Feb 11;22(4):1785. doi: 10.3390/ijms22041785.
2
Ex Vivo Live Full-Thickness Porcine Skin Model as a Versatile In Vitro Testing Method for Skin Barrier Research.离体全层猪皮模型作为一种用于皮肤屏障研究的多功能体外测试方法。
Int J Mol Sci. 2021 Jan 11;22(2):657. doi: 10.3390/ijms22020657.
3
miR-155 Contributes to Normal Keratinocyte Differentiation and Is Upregulated in the Epidermis of Psoriatic Skin Lesions.miR-155 有助于正常角质形成细胞分化，并在银屑病皮损的表皮中上调。
Int J Mol Sci. 2020 Dec 5;21(23):9288. doi: 10.3390/ijms21239288.
4
Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging.细胞外基质完整性与皮肤老化过程中 tenascin C 的作用
Int J Mol Sci. 2020 Nov 18;21(22):8693. doi: 10.3390/ijms21228693.
5
Weak Ultraviolet B Enhances the Mislocalization of Claudin-1 Mediated by Nitric Oxide and Peroxynitrite Production in Human Keratinocyte-Derived HaCaT Cells.弱紫外线 B 增强一氧化氮和过氧亚硝酸盐产生介导的 Claudin-1 在人角质形成细胞源性 HaCaT 细胞中的错误定位。
Int J Mol Sci. 2020 Sep 27;21(19):7138. doi: 10.3390/ijms21197138.
6
The Role of MicroRNAs in Epidermal Barrier.微小 RNA 在表皮屏障中的作用。
Int J Mol Sci. 2020 Aug 12;21(16):5781. doi: 10.3390/ijms21165781.
7
Synthetic Retinoid Seletinoid G Improves Skin Barrier Function through Wound Healing and Collagen Realignment in Human Skin Equivalents.合成维 A 类似物 Seletinoid G 通过促进伤口愈合和胶原重排改善人皮肤等效物的皮肤屏障功能。
Int J Mol Sci. 2020 Apr 30;21(9):3198. doi: 10.3390/ijms21093198.
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Skin Barrier Abnormalities and Immune Dysfunction in Atopic Dermatitis.特应性皮炎的皮肤屏障异常和免疫功能障碍。
Int J Mol Sci. 2020 Apr 20;21(8):2867. doi: 10.3390/ijms21082867.
9
Anti-Aging Effects of GDF11 on Skin.GDF11 对皮肤的抗衰老作用。
Int J Mol Sci. 2020 Apr 9;21(7):2598. doi: 10.3390/ijms21072598.
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ethanol extract inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in NC/Nga mice and TNF-α/IFN-γ-induced TARC expression in HaCaT cells.乙醇提取物可抑制NC/Nga小鼠中2,4-二硝基氯苯诱导的特应性皮炎样皮肤损伤以及HaCaT细胞中肿瘤坏死因子-α/干扰素-γ诱导的胸腺活化调节趋化因子表达。
Toxicol Res. 2019 Nov 26;36(2):99-108. doi: 10.1007/s43188-019-00026-0. eCollection 2020 Apr.

皮肤表皮与屏障功能。

Skin Epidermis and Barrier Function.

机构信息

College of Pharmacy, Ewha Womans University, Seodaemungu, Seoul 03760, Korea.

出版信息

Int J Mol Sci. 2021 Mar 16;22(6):3035. doi: 10.3390/ijms22063035.

DOI:10.3390/ijms22063035
PMID:33809733
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8002265/
Abstract

The skin epidermis is the outermost epithelial tissue that protects the body from the external environment [...].

摘要

皮肤表皮是最外层的上皮组织，保护身体免受外部环境的影响[...]。