School of Nursing, Kaohsiung Medical University, Taiwan.
Department of Surgical Nursing, STIkes, Santa Elisabeth Medan, Indonesia.
Geriatr Nurs. 2021 Sep-Oct;42(5):1230-1239. doi: 10.1016/j.gerinurse.2021.03.007. Epub 2021 Mar 14.
The purpose of this study was to systematically examine the association between dementia and mortality among older adults with COVID-19. To do so, we conducted a search of 7 databases for relevant full-text articles. A cohort study and case-control study were included. A meta-analysis was performed to synthesize the pooled odds ratio with a random-effects model. We identified studies that reported mortality among older adults with dementia and non-dementia who have COVID-19. The pooled mortality rates of dementia and non-dementia older adults infected with COVID-19 were 39% (95% CI: 0.23-0.54%, I = 83.48%) and 20% (95% CI: 0.16-0.25%, I = 83.48%), respectively. Overall, dementia was the main factor influencing poor health outcomes and high rates of mortality in older adults with COVID-19 infection (odds ratio 2.96; 95% CI 2.00-4.38, I = 29.7%), respectively. Our results show that older adults with dementia with COVID-19 infection have a higher risk of mortality compared with older adults without dementia. This current study further highlights the need to provide focused care to the older adults with dementia or cognitive impairment who have COVID-19.
本研究旨在系统地检查 COVID-19 老年患者痴呆症与死亡率之间的关联。为此，我们对 7 个数据库进行了相关全文文章的检索。包括队列研究和病例对照研究。采用随机效应模型进行荟萃分析，综合汇总优势比。我们确定了报告 COVID-19 痴呆和非痴呆老年患者死亡率的研究。感染 COVID-19 的痴呆和非痴呆老年患者的合并死亡率分别为 39%（95%CI：0.23-0.54%，I=83.48%）和 20%（95%CI：0.16-0.25%，I=83.48%）。总体而言，痴呆症是影响 COVID-19 感染老年患者健康结局不良和高死亡率的主要因素（优势比 2.96；95%CI 2.00-4.38，I=29.7%）。我们的研究结果表明，与无痴呆症的 COVID-19 感染老年患者相比，患有痴呆症的老年患者的死亡率更高。本研究进一步强调了需要为 COVID-19 感染的痴呆或认知障碍老年患者提供有针对性的护理。
