Prescott M J
National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), 20 Park Crescent, London, W1B 1AL, UK.
Adv Sci Res. 2010 Nov;5(1):11-22. doi: 10.5194/asr-5-11-2010. Epub 2010 Nov 12.
This article provides an overview of the ethical issues raised by the use of non-human primates (NHPs) in research involving scientific procedures which may cause pain, suffering, distress or lasting harm. It is not an exhaustive review of the literature and views on this subject, and it does not present any conclusions about the moral acceptability or otherwise of NHP research. Rather the aim has been to identify the ethical issues involved and to provide guidance on how these might be addressed, in particular by carefully examining the scientific rationale for NHP use, implementing fully the 3Rs principle of Russell and Burch (1959) and applying a robust "harm-benefit assessment" to research proposals involving NHPs.
本文概述了在涉及可能导致疼痛、痛苦、不适或持久伤害的科学程序的研究中使用非人类灵长类动物(NHPs)所引发的伦理问题。它并非对该主题的文献和观点进行详尽回顾,也未就NHPs研究在道德上是否可接受给出任何结论。相反,其目的在于识别其中涉及的伦理问题,并就如何解决这些问题提供指导,特别是通过仔细审查使用NHPs的科学依据、全面实施罗素和伯奇(1959年)的3R原则,以及对涉及NHPs的研究提案进行严格的“危害-益处评估”。