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农田使用氢氧化钙作为一种有效的病原体阻隔剂。

Farm use of calcium hydroxide as an effective barrier against pathogens.

机构信息

Department of Applied Science, Muroran Institute of Technology, Muroran, Hokkaido, Japan.

出版信息

Sci Rep. 2021 Apr 12;11(1):7941. doi: 10.1038/s41598-021-86796-w.

DOI:10.1038/s41598-021-86796-w
PMID:33846406
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8041792/
Abstract

Livestock farming is affected by the occurrence of infectious diseases, but outbreaks can be prevented by proper sanitary control measures. Calcium hydroxide (Ca(OH)), commonly called slaked lime, powder is traditionally used as a disinfectant to prevent infectious diseases in livestock. Since Ca(OH) can inactivate a wide variety of pathogens, has a small environmental impact, does not require a disinfection tank (i.e., can be spread directly on the ground) and is produced inexpensively worldwide, it is used for the prevention of epidemics on farms worldwide. Water is essential for the strong alkalinity that underlies its disinfecting effect, but it is unknown how much water is required under field conditions. In addition, Ca(OH) reacts with carbon dioxide in the environment, reducing its pH, but it is unclear how long its degradation takes under actual field use. Thus, we measured the water adsorption ability of Ca(OH)-based disinfectants and its relation to disinfectant activity, as assessed by colony counts and live/dead staining and observation. We found that 15-20% (w/w) water in Ca(OH) was necessary for disinfection to occur in practice. Moreover, we found that the pH of Ca(OH) decreased within about two weeks to one month under actual use in practical conditions and lost its ability to disinfect. We further showed that granules prepared from Ca(OH) and zeolite maintained high alkalinity more than twice as long as calcium powder. These findings will help to establish a suitable method of applying Ca(OH) to protect farms from infectious diseases.

摘要

畜牧业受到传染病发生的影响,但通过适当的卫生控制措施可以预防疫情爆发。氢氧化钙(Ca(OH)),通常称为熟石灰,粉末传统上用作消毒剂,以预防牲畜中的传染病。由于 Ca(OH) 可以灭活多种病原体,对环境的影响较小,不需要消毒池(即可以直接撒在地上),并且在全球范围内廉价生产,因此它被用于预防世界各地农场的流行病。水是其消毒效果的强碱性的基础,但在田间条件下需要多少水尚不清楚。此外,Ca(OH) 与环境中的二氧化碳反应,降低其 pH 值,但不清楚在实际田间使用下其降解需要多长时间。因此,我们测量了基于 Ca(OH) 的消毒剂的水吸附能力及其与消毒剂活性的关系,通过菌落计数和死活染色和观察进行评估。我们发现,在实践中,Ca(OH) 中 15-20%(w/w)的水是消毒所必需的。此外,我们发现,在实际使用条件下,Ca(OH) 的 pH 值在大约两周到一个月内降至一个月,并且失去了消毒能力。我们进一步表明,由 Ca(OH) 和沸石制备的颗粒保持高碱性的时间是钙粉的两倍以上。这些发现将有助于建立一种合适的方法来应用 Ca(OH) 以保护农场免受传染病的侵害。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d18c/8041792/cf60f1abcf1b/41598_2021_86796_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d18c/8041792/561fc7bdcf30/41598_2021_86796_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d18c/8041792/4694efbc08ea/41598_2021_86796_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d18c/8041792/63a648747ed1/41598_2021_86796_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d18c/8041792/2c0d3999c0a0/41598_2021_86796_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d18c/8041792/cf60f1abcf1b/41598_2021_86796_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d18c/8041792/561fc7bdcf30/41598_2021_86796_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d18c/8041792/4694efbc08ea/41598_2021_86796_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d18c/8041792/63a648747ed1/41598_2021_86796_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d18c/8041792/2c0d3999c0a0/41598_2021_86796_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d18c/8041792/cf60f1abcf1b/41598_2021_86796_Fig5_HTML.jpg

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