School of Public Health, Texas A&M University, College Station, TX, United Stated of America.
Department of Statistics, Texas A&M University, College Station, TX, United Stated of America.
PLoS One. 2021 Apr 14;16(4):e0250110. doi: 10.1371/journal.pone.0250110. eCollection 2021.
Prediction of the dynamics of new SARS-CoV-2 infections during the current COVID-19 pandemic is critical for public health planning of efficient health care allocation and monitoring the effects of policy interventions. We describe a new approach that forecasts the number of incident cases in the near future given past occurrences using only a small number of assumptions.
Our approach to forecasting future COVID-19 cases involves 1) modeling the observed incidence cases using a Poisson distribution for the daily incidence number, and a gamma distribution for the series interval; 2) estimating the effective reproduction number assuming its value stays constant during a short time interval; and 3) drawing future incidence cases from their posterior distributions, assuming that the current transmission rate will stay the same, or change by a certain degree.
We apply our method to predicting the number of new COVID-19 cases in a single state in the U.S. and for a subset of counties within the state to demonstrate the utility of this method at varying scales of prediction. Our method produces reasonably accurate results when the effective reproduction number is distributed similarly in the future as in the past. Large deviations from the predicted results can imply that a change in policy or some other factors have occurred that have dramatically altered the disease transmission over time.
We presented a modelling approach that we believe can be easily adopted by others, and immediately useful for local or state planning.
预测当前 COVID-19 大流行期间新 SARS-CoV-2 感染的动态对于公共卫生规划有效分配医疗资源和监测政策干预效果至关重要。我们描述了一种新方法,该方法仅使用少量假设,根据过去的情况预测近期的发病数。
我们预测未来 COVID-19 病例的方法包括:1)使用泊松分布对每日发病数进行建模,使用伽马分布对序列间隔进行建模;2)假设在短时间间隔内有效繁殖数保持不变,对其进行估计;3)假设当前传播率保持不变或变化一定程度,从其后验分布中抽取未来的发病数。
我们将我们的方法应用于预测美国一个州和该州内一些县的新 COVID-19 病例数,以展示该方法在不同预测规模下的实用性。当有效繁殖数在未来的分布与过去相似时,我们的方法产生了相当准确的结果。预测结果的较大偏差可能意味着政策或其他因素发生了变化,这些变化极大地改变了疾病随时间的传播。
我们提出了一种建模方法,我们相信其他人可以很容易地采用,并立即为地方或州规划提供有用的信息。